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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ETS1
All Species:
29.39
Human Site:
Y185
Identified Species:
53.89
UniProt:
P14921
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14921
NP_005229.1
441
50408
Y185
P
S
F
I
T
E
S
Y
Q
T
L
H
P
I
S
Chimpanzee
Pan troglodytes
XP_001170891
731
79148
P475
G
M
Q
T
Q
N
Y
P
K
G
G
L
L
D
S
Rhesus Macaque
Macaca mulatta
XP_001113198
441
50116
Y185
P
S
F
I
T
E
S
Y
Q
T
L
H
P
I
S
Dog
Lupus familis
XP_546405
441
50378
Y185
P
S
F
I
T
E
S
Y
Q
T
L
H
P
I
S
Cat
Felis silvestris
Mouse
Mus musculus
P27577
440
50183
Y185
P
S
F
I
T
E
S
Y
Q
T
L
H
P
I
S
Rat
Rattus norvegicus
P41156
441
50404
Y185
P
S
F
I
T
E
S
Y
Q
T
L
H
P
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508979
473
53725
K217
M
Q
T
P
S
Y
P
K
M
S
L
L
D
G
V
Chicken
Gallus gallus
P13474
441
50308
Y185
P
S
F
I
T
E
S
Y
Q
T
L
H
P
I
S
Frog
Xenopus laevis
P18755
438
50249
Y182
P
S
F
I
T
E
S
Y
Q
T
L
H
P
I
S
Zebra Danio
Brachydanio rerio
Q9PUQ1
494
55602
S185
S
Q
S
H
A
C
H
S
H
S
Y
P
M
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P51022
623
66848
L191
A
N
N
L
V
G
A
L
S
S
S
T
A
A
S
Honey Bee
Apis mellifera
XP_396368
484
53763
Y226
L
D
G
S
P
E
F
Y
S
T
S
G
I
H
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999698
559
62034
T240
S
V
T
T
T
T
T
T
T
A
S
S
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.4
95.9
99
N.A.
97
98.8
N.A.
52.2
95.9
88.6
23.4
N.A.
28.4
32
N.A.
38.1
Protein Similarity:
100
43.2
96.8
99.5
N.A.
98.4
99.3
N.A.
66.5
97.7
93.8
37.6
N.A.
41
42.5
N.A.
50.8
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
6.6
100
100
0
N.A.
6.6
20
N.A.
13.3
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
20
100
100
6.6
N.A.
33.3
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
8
0
0
8
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
8
8
0
% D
% Glu:
0
0
0
0
0
62
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
54
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
0
8
0
0
0
8
8
8
0
8
0
% G
% His:
0
0
0
8
0
0
8
0
8
0
0
54
0
8
0
% H
% Ile:
0
0
0
54
0
0
0
0
0
0
0
0
8
54
0
% I
% Lys:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% K
% Leu:
8
0
0
8
0
0
0
8
0
0
62
16
8
0
8
% L
% Met:
8
8
0
0
0
0
0
0
8
0
0
0
8
0
0
% M
% Asn:
0
8
8
0
0
8
0
0
0
0
0
0
0
8
0
% N
% Pro:
54
0
0
8
8
0
8
8
0
0
0
8
54
0
8
% P
% Gln:
0
16
8
0
8
0
0
0
54
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
16
54
8
8
8
0
54
8
16
24
24
8
8
8
77
% S
% Thr:
0
0
16
16
62
8
8
8
8
62
0
8
0
0
0
% T
% Val:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
62
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _