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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIF
All Species:
14.24
Human Site:
Y168
Identified Species:
44.76
UniProt:
P15018
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15018
NP_002300.1
202
22008
Y168
V
G
H
V
D
V
T
Y
G
P
D
T
S
G
K
Chimpanzee
Pan troglodytes
XP_001140005
158
17347
K131
Y
G
P
D
T
S
G
K
D
V
F
Q
K
K
K
Rhesus Macaque
Macaca mulatta
XP_001108593
202
21978
Y168
V
G
H
V
D
V
T
Y
G
P
D
T
S
G
K
Dog
Lupus familis
XP_534732
202
22008
Y168
V
A
H
V
D
V
A
Y
G
P
D
T
S
G
K
Cat
Felis silvestris
Mouse
Mus musculus
P09056
203
22269
P169
V
G
H
V
D
V
P
P
V
P
D
H
S
D
K
Rat
Rattus norvegicus
P17777
202
22094
C168
V
G
H
V
D
V
P
C
V
P
D
N
S
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512128
291
31626
Y160
V
F
H
V
D
V
T
Y
G
S
Y
S
R
E
K
Chicken
Gallus gallus
XP_425293
217
24143
Y176
I
F
Q
V
D
V
S
Y
G
E
S
S
K
D
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.2
99
92
N.A.
79.8
82.6
N.A.
42.6
42.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
78.2
99.5
96.5
N.A.
88.6
90.5
N.A.
51.5
58
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
86.6
N.A.
66.6
66.6
N.A.
60
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
86.6
N.A.
66.6
66.6
N.A.
66.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
0
0
0
13
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
13
88
0
0
0
13
0
63
0
0
25
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
13
0
0
0
13
0
% E
% Phe:
0
25
0
0
0
0
0
0
0
0
13
0
0
0
0
% F
% Gly:
0
63
0
0
0
0
13
0
63
0
0
0
0
38
0
% G
% His:
0
0
75
0
0
0
0
0
0
0
0
13
0
0
0
% H
% Ile:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
13
0
0
0
0
25
13
100
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% N
% Pro:
0
0
13
0
0
0
25
13
0
63
0
0
0
0
0
% P
% Gln:
0
0
13
0
0
0
0
0
0
0
0
13
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% R
% Ser:
0
0
0
0
0
13
13
0
0
13
13
25
63
13
0
% S
% Thr:
0
0
0
0
13
0
38
0
0
0
0
38
0
0
0
% T
% Val:
75
0
0
88
0
88
0
0
25
13
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
0
0
0
0
63
0
0
13
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _