KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRAF
All Species:
16.06
Human Site:
T332
Identified Species:
25.24
UniProt:
P15056
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15056
NP_004324.2
766
84437
T332
S
I
G
P
Q
I
L
T
S
P
S
P
S
K
S
Chimpanzee
Pan troglodytes
XP_001155024
767
84561
T332
S
I
G
P
Q
I
L
T
S
P
S
P
S
K
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532749
767
85780
P301
P
S
P
S
K
S
I
P
I
P
Q
P
F
R
P
Cat
Felis silvestris
Mouse
Mus musculus
P28028
804
88899
S316
T
G
P
Q
I
L
T
S
P
S
P
S
K
S
I
Rat
Rattus norvegicus
P11345
648
72910
L251
S
P
S
S
E
G
S
L
S
Q
R
Q
R
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516512
799
90020
A312
S
I
G
P
P
I
V
A
S
P
S
P
S
K
S
Chicken
Gallus gallus
Q04982
806
89347
P332
S
V
G
P
P
I
L
P
S
P
S
P
S
K
S
Frog
Xenopus laevis
P09560
638
71941
P241
H
P
F
S
F
S
T
P
S
P
V
S
E
C
S
Zebra Danio
Brachydanio rerio
NP_991307
777
86403
P342
S
T
G
S
L
C
H
P
T
V
S
P
S
K
S
Tiger Blowfish
Takifugu rubipres
NP_001032957
778
86510
S342
S
T
G
S
I
C
Q
S
T
V
S
P
S
K
S
Fruit Fly
Dros. melanogaster
P11346
782
88616
S356
S
R
S
R
R
C
S
S
S
G
S
S
S
S
S
Honey Bee
Apis mellifera
XP_396892
715
80060
S309
G
Q
Q
D
R
S
S
S
A
P
N
V
C
F
N
Nematode Worm
Caenorhab. elegans
Q07292
813
90389
S369
F
Q
S
G
H
I
L
S
G
A
R
M
N
R
L
Sea Urchin
Strong. purpuratus
XP_781094
750
85072
S328
N
T
L
P
R
E
R
S
T
S
A
P
N
I
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q05609
821
90288
L362
L
C
R
H
R
A
L
L
F
K
V
L
A
D
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
N.A.
92.9
N.A.
88.8
50.2
N.A.
85.7
89.8
49.3
83.5
82.9
42.8
50.6
30.7
49.3
Protein Similarity:
100
99.3
N.A.
93.4
N.A.
89.3
62.2
N.A.
86.7
90.9
61.3
87.5
87.1
57.9
65
46.6
62.6
P-Site Identity:
100
100
N.A.
13.3
N.A.
0
13.3
N.A.
80
80
20
46.6
46.6
33.3
6.6
13.3
13.3
P-Site Similarity:
100
100
N.A.
33.3
N.A.
20
26.6
N.A.
86.6
86.6
20
53.3
60
46.6
40
33.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
7
7
7
7
0
7
0
0
% A
% Cys:
0
7
0
0
0
20
0
0
0
0
0
0
7
7
7
% C
% Asp:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% D
% Glu:
0
0
0
0
7
7
0
0
0
0
0
0
7
0
0
% E
% Phe:
7
0
7
0
7
0
0
0
7
0
0
0
7
7
0
% F
% Gly:
7
7
40
7
0
7
0
0
7
7
0
0
0
0
0
% G
% His:
7
0
0
7
7
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
20
0
0
14
34
7
0
7
0
0
0
0
7
14
% I
% Lys:
0
0
0
0
7
0
0
0
0
7
0
0
7
40
0
% K
% Leu:
7
0
7
0
7
7
34
14
0
0
0
7
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
7
0
0
0
0
0
0
0
0
0
7
0
14
0
7
% N
% Pro:
7
14
14
34
14
0
0
27
7
47
7
54
0
0
7
% P
% Gln:
0
14
7
7
14
0
7
0
0
7
7
7
0
0
0
% Q
% Arg:
0
7
7
7
27
0
7
0
0
0
14
0
7
14
0
% R
% Ser:
54
7
20
34
0
20
20
40
47
14
47
20
47
20
54
% S
% Thr:
7
20
0
0
0
0
14
14
20
0
0
0
0
0
7
% T
% Val:
0
7
0
0
0
0
7
0
0
14
14
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _