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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRAF
All Species:
25.15
Human Site:
T411
Identified Species:
39.52
UniProt:
P15056
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15056
NP_004324.2
766
84437
T411
A
S
L
P
G
S
L
T
N
V
K
A
L
Q
K
Chimpanzee
Pan troglodytes
XP_001155024
767
84561
T411
A
S
L
P
G
S
L
T
N
V
K
A
L
Q
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532749
767
85780
T411
A
S
L
P
G
S
L
T
N
V
K
A
L
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
P28028
804
88899
V448
L
P
G
S
L
T
N
V
K
A
L
Q
K
S
P
Rat
Rattus norvegicus
P11345
648
72910
Q315
P
K
T
P
V
P
A
Q
R
E
R
A
P
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516512
799
90020
T443
A
S
L
P
G
S
L
T
N
V
K
A
L
Q
K
Chicken
Gallus gallus
Q04982
806
89347
T451
A
S
L
P
G
S
L
T
N
V
K
A
L
Q
K
Frog
Xenopus laevis
P09560
638
71941
T305
N
A
K
A
P
A
P
T
H
R
E
K
A
A
S
Zebra Danio
Brachydanio rerio
NP_991307
777
86403
L421
P
A
S
L
P
G
S
L
P
N
V
K
V
S
K
Tiger Blowfish
Takifugu rubipres
NP_001032957
778
86510
T422
A
S
L
P
G
S
L
T
N
V
K
V
P
Q
K
Fruit Fly
Dros. melanogaster
P11346
782
88616
N426
H
P
C
T
D
H
S
N
S
T
Q
A
S
P
T
Honey Bee
Apis mellifera
XP_396892
715
80060
R374
T
L
R
P
K
R
P
R
A
R
S
A
D
E
S
Nematode Worm
Caenorhab. elegans
Q07292
813
90389
Q435
T
L
P
L
T
P
P
Q
S
A
P
P
Q
K
I
Sea Urchin
Strong. purpuratus
XP_781094
750
85072
T394
H
S
S
Q
P
S
P
T
H
Q
P
R
W
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q05609
821
90288
P434
I
S
S
P
L
R
F
P
R
P
K
P
V
E
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
N.A.
92.9
N.A.
88.8
50.2
N.A.
85.7
89.8
49.3
83.5
82.9
42.8
50.6
30.7
49.3
Protein Similarity:
100
99.3
N.A.
93.4
N.A.
89.3
62.2
N.A.
86.7
90.9
61.3
87.5
87.1
57.9
65
46.6
62.6
P-Site Identity:
100
100
N.A.
100
N.A.
0
13.3
N.A.
100
100
6.6
6.6
86.6
6.6
13.3
0
20
P-Site Similarity:
100
100
N.A.
100
N.A.
6.6
20
N.A.
100
100
33.3
20
86.6
20
20
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
14
0
7
0
7
7
0
7
14
0
54
7
7
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
7
% D
% Glu:
0
0
0
0
0
0
0
0
0
7
7
0
0
14
0
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
40
7
0
0
0
0
0
0
0
7
0
% G
% His:
14
0
0
0
0
7
0
0
14
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% I
% Lys:
0
7
7
0
7
0
0
0
7
0
47
14
7
14
47
% K
% Leu:
7
14
40
14
14
0
40
7
0
0
7
0
34
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
7
7
40
7
0
0
0
0
0
% N
% Pro:
14
14
7
60
20
14
27
7
7
7
14
14
14
7
14
% P
% Gln:
0
0
0
7
0
0
0
14
0
7
7
7
7
40
0
% Q
% Arg:
0
0
7
0
0
14
0
7
14
14
7
7
0
0
0
% R
% Ser:
0
54
20
7
0
47
14
0
14
0
7
0
7
14
20
% S
% Thr:
14
0
7
7
7
7
0
54
0
7
0
0
0
0
7
% T
% Val:
0
0
0
0
7
0
0
7
0
40
7
7
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _