KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRAF
All Species:
42.42
Human Site:
T599
Identified Species:
66.67
UniProt:
P15056
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15056
NP_004324.2
766
84437
T599
I
G
D
F
G
L
A
T
V
K
S
R
W
S
G
Chimpanzee
Pan troglodytes
XP_001155024
767
84561
T599
I
G
D
F
G
L
A
T
V
K
S
R
W
S
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532749
767
85780
T599
I
G
D
F
G
L
A
T
V
K
S
R
W
S
G
Cat
Felis silvestris
Mouse
Mus musculus
P28028
804
88899
T636
I
G
D
F
G
L
A
T
V
K
S
R
W
S
G
Rat
Rattus norvegicus
P11345
648
72910
Q500
K
S
R
W
S
G
S
Q
Q
V
E
Q
P
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516512
799
90020
T631
I
G
D
F
G
L
A
T
V
K
S
R
W
S
G
Chicken
Gallus gallus
Q04982
806
89347
T639
I
G
D
F
G
L
A
T
V
K
S
R
W
S
G
Frog
Xenopus laevis
P09560
638
71941
S490
V
K
T
R
W
S
G
S
Q
Q
V
E
Q
L
T
Zebra Danio
Brachydanio rerio
NP_991307
777
86403
T609
I
G
D
F
G
L
A
T
V
K
S
R
W
S
G
Tiger Blowfish
Takifugu rubipres
NP_001032957
778
86510
T610
I
G
D
F
G
L
A
T
V
K
S
R
W
S
G
Fruit Fly
Dros. melanogaster
P11346
782
88616
T614
I
G
D
F
G
L
A
T
A
K
T
R
W
S
G
Honey Bee
Apis mellifera
XP_396892
715
80060
G560
Q
Q
F
H
Q
P
T
G
S
I
L
W
M
A
P
Nematode Worm
Caenorhab. elegans
Q07292
813
90389
G623
T
V
K
I
G
D
F
G
L
A
T
V
K
T
K
Sea Urchin
Strong. purpuratus
XP_781094
750
85072
T582
I
G
D
F
G
L
A
T
V
K
S
R
W
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q05609
821
90288
T625
P
P
N
L
S
I
V
T
E
Y
L
S
R
G
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
N.A.
92.9
N.A.
88.8
50.2
N.A.
85.7
89.8
49.3
83.5
82.9
42.8
50.6
30.7
49.3
Protein Similarity:
100
99.3
N.A.
93.4
N.A.
89.3
62.2
N.A.
86.7
90.9
61.3
87.5
87.1
57.9
65
46.6
62.6
P-Site Identity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
100
100
0
100
100
86.6
0
6.6
100
P-Site Similarity:
100
100
N.A.
100
N.A.
100
33.3
N.A.
100
100
20
100
100
93.3
6.6
26.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
67
0
7
7
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
67
0
0
7
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
7
0
7
7
0
0
0
% E
% Phe:
0
0
7
67
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
67
0
0
74
7
7
14
0
0
0
0
0
7
74
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
67
0
0
7
0
7
0
0
0
7
0
0
0
0
0
% I
% Lys:
7
7
7
0
0
0
0
0
0
67
0
0
7
0
7
% K
% Leu:
0
0
0
7
0
67
0
0
7
0
14
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
7
7
0
0
0
7
0
0
0
0
0
0
7
0
7
% P
% Gln:
7
7
0
0
7
0
0
7
14
7
0
7
7
0
0
% Q
% Arg:
0
0
7
7
0
0
0
0
0
0
0
67
7
0
0
% R
% Ser:
0
7
0
0
14
7
7
7
7
0
60
7
0
67
7
% S
% Thr:
7
0
7
0
0
0
7
74
0
0
14
0
0
14
7
% T
% Val:
7
7
0
0
0
0
7
0
60
7
7
7
0
0
0
% V
% Trp:
0
0
0
7
7
0
0
0
0
0
0
7
67
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _