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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPA1 All Species: 8.79
Human Site: S61 Identified Species: 16.11
UniProt: P15085 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P15085 NP_001859.1 419 47140 S61 R G P A H P G S P I D V R V P
Chimpanzee Pan troglodytes XP_001145510 852 95546 E494 V Q K V K E L E D L P Q L D F
Rhesus Macaque Macaca mulatta XP_001096893 419 47031 S61 R G P A H P G S P I D V R V P
Dog Lupus familis XP_532424 416 46575 S61 R G P G R P G S P I D V R V P
Cat Felis silvestris
Mouse Mus musculus Q7TPZ8 419 47366 L61 R D P A R A G L P I D V R V P
Rat Rattus norvegicus P00731 419 47179 I61 R D A A R A G I P I D V R V P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510426 393 44214 P38 G P A N P S S P I D V R V P F
Chicken Gallus gallus NP_989915 419 46988 P63 S P R G L G N P V D I R V P F
Frog Xenopus laevis NP_001088499 420 47261 P62 S P T K V L L P I D I R V S F
Zebra Danio Brachydanio rerio NP_954965 419 47680 S61 W M E P I L E S L P L D L H V
Tiger Blowfish Takifugu rubipres NP_001163829 452 50806 L94 M I E D L Q V L L D E E Q E G
Fruit Fly Dros. melanogaster Q9VL86 430 47642 A67 D G V H L V G A D I Q I I V A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38836 430 49811 N64 Y D V W T R S N N F I D I K L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.3 95.4 88.3 N.A. 81.8 83.5 N.A. 72.3 71.8 66.6 64.4 62.6 33.2 N.A. N.A. N.A.
Protein Similarity: 100 47.8 98 92.5 N.A. 89.9 91.1 N.A. 81.6 82.5 80.2 77.5 73.8 57.2 N.A. N.A. N.A.
P-Site Identity: 100 0 100 86.6 N.A. 73.3 66.6 N.A. 0 0 0 6.6 0 26.6 N.A. N.A. N.A.
P-Site Similarity: 100 6.6 100 86.6 N.A. 73.3 66.6 N.A. 0 0 0 6.6 13.3 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 31 0 16 0 8 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 24 0 8 0 0 0 0 16 31 39 16 0 8 0 % D
% Glu: 0 0 16 0 0 8 8 8 0 0 8 8 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 31 % F
% Gly: 8 31 0 16 0 8 47 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 8 16 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 8 0 0 8 0 0 8 16 47 24 8 16 0 0 % I
% Lys: 0 0 8 8 8 0 0 0 0 0 0 0 0 8 0 % K
% Leu: 0 0 0 0 24 16 16 16 16 8 8 0 16 0 8 % L
% Met: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 8 8 8 0 0 0 0 0 0 % N
% Pro: 0 24 31 8 8 24 0 24 39 8 8 0 0 16 39 % P
% Gln: 0 8 0 0 0 8 0 0 0 0 8 8 8 0 0 % Q
% Arg: 39 0 8 0 24 8 0 0 0 0 0 24 39 0 0 % R
% Ser: 16 0 0 0 0 8 16 31 0 0 0 0 0 8 0 % S
% Thr: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % T
% Val: 8 0 16 8 8 8 8 0 8 0 8 39 24 47 8 % V
% Trp: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _