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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANPEP
All Species:
18.18
Human Site:
S220
Identified Species:
30.77
UniProt:
P15144
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15144
NP_001141.2
967
109540
S220
Q
A
A
D
A
R
K
S
F
P
C
F
D
E
P
Chimpanzee
Pan troglodytes
XP_523153
967
109577
S220
Q
A
A
D
A
R
K
S
F
P
C
F
D
E
P
Rhesus Macaque
Macaca mulatta
XP_001093727
968
109887
S221
Q
A
A
D
A
R
K
S
F
P
C
F
D
E
P
Dog
Lupus familis
XP_859826
931
105294
L213
E
N
G
V
K
K
V
L
A
T
T
Q
M
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
P97449
966
109633
S220
Q
A
A
D
A
R
K
S
F
P
C
F
D
E
P
Rat
Rattus norvegicus
P15684
965
109430
S220
Q
A
A
D
A
R
K
S
F
P
C
F
D
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514698
839
94749
I121
C
K
E
P
T
D
V
I
I
I
H
S
K
K
L
Chicken
Gallus gallus
NP_990192
967
108652
F220
A
P
D
A
R
K
A
F
P
C
F
D
E
P
A
Frog
Xenopus laevis
NP_001088591
963
109575
C220
D
A
R
K
A
F
P
C
F
D
E
P
A
M
K
Zebra Danio
Brachydanio rerio
XP_001340256
965
110120
A220
Q
A
T
D
A
R
K
A
F
P
C
F
D
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651674
999
115252
A244
H
N
E
T
R
W
V
A
S
T
Q
F
Q
A
T
Honey Bee
Apis mellifera
XP_396261
982
112493
A233
Q
P
T
D
A
R
R
A
F
P
C
F
D
E
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783617
1060
120846
A309
Q
P
T
D
A
R
R
A
L
P
C
F
D
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37898
856
97644
A139
E
A
T
D
A
R
R
A
F
P
C
F
D
E
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
95.3
75.4
N.A.
76.3
77.8
N.A.
60.5
66.1
59
60.3
N.A.
35.6
37.2
N.A.
38.2
Protein Similarity:
100
99.4
97.9
85.1
N.A.
87.1
88.1
N.A.
70.4
78.8
74.2
74.9
N.A.
55.2
58.6
N.A.
57
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
0
0
20
86.6
N.A.
6.6
73.3
N.A.
66.6
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
6.6
13.3
20
93.3
N.A.
13.3
86.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
58
36
8
72
0
8
36
8
0
0
0
8
8
15
% A
% Cys:
8
0
0
0
0
0
0
8
0
8
65
0
0
0
0
% C
% Asp:
8
0
8
65
0
8
0
0
0
8
0
8
65
0
0
% D
% Glu:
15
0
15
0
0
0
0
0
0
0
8
0
8
65
0
% E
% Phe:
0
0
0
0
0
8
0
8
65
0
8
72
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
8
8
0
0
0
0
0
% I
% Lys:
0
8
0
8
8
15
43
0
0
0
0
0
8
8
8
% K
% Leu:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% M
% Asn:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
22
0
8
0
0
8
0
8
65
0
8
0
8
65
% P
% Gln:
58
0
0
0
0
0
0
0
0
0
8
8
8
8
0
% Q
% Arg:
0
0
8
0
15
65
22
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
36
8
0
0
8
0
0
0
% S
% Thr:
0
0
29
8
8
0
0
0
0
15
8
0
0
0
8
% T
% Val:
0
0
0
8
0
0
22
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _