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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANPEP
All Species:
17.58
Human Site:
S247
Identified Species:
29.74
UniProt:
P15144
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15144
NP_001141.2
967
109540
S247
P
K
D
L
T
A
L
S
N
M
L
P
K
G
P
Chimpanzee
Pan troglodytes
XP_523153
967
109577
S247
P
K
D
L
T
A
L
S
N
M
L
P
K
G
P
Rhesus Macaque
Macaca mulatta
XP_001093727
968
109887
S248
P
K
D
L
T
A
L
S
N
M
L
P
K
G
P
Dog
Lupus familis
XP_859826
931
105294
F239
E
P
A
M
K
A
T
F
N
I
T
L
I
H
P
Cat
Felis silvestris
Mouse
Mus musculus
P97449
966
109633
L246
Y
P
N
N
L
I
A
L
S
N
M
L
P
K
E
Rat
Rattus norvegicus
P15684
965
109430
L246
H
P
N
N
L
T
A
L
S
N
M
L
P
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514698
839
94749
A147
T
L
K
G
L
E
G
A
T
S
P
T
T
K
S
Chicken
Gallus gallus
NP_990192
967
108652
S246
P
S
D
H
T
A
I
S
N
M
P
V
H
S
T
Frog
Xenopus laevis
NP_001088591
963
109575
Q247
Y
K
A
M
S
N
M
Q
D
I
E
T
K
T
E
Zebra Danio
Brachydanio rerio
XP_001340256
965
110120
L246
H
D
P
G
T
V
A
L
S
N
G
V
V
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651674
999
115252
R275
N
F
T
L
H
I
A
R
P
R
N
M
T
T
I
Honey Bee
Apis mellifera
XP_396261
982
112493
S260
P
K
N
M
T
S
I
S
N
M
P
Q
M
G
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783617
1060
120846
S336
R
D
D
M
V
A
L
S
N
G
I
E
E
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37898
856
97644
L165
S
E
S
F
L
T
H
L
S
N
M
D
V
R
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
95.3
75.4
N.A.
76.3
77.8
N.A.
60.5
66.1
59
60.3
N.A.
35.6
37.2
N.A.
38.2
Protein Similarity:
100
99.4
97.9
85.1
N.A.
87.1
88.1
N.A.
70.4
78.8
74.2
74.9
N.A.
55.2
58.6
N.A.
57
P-Site Identity:
100
100
100
20
N.A.
0
0
N.A.
0
46.6
13.3
6.6
N.A.
6.6
46.6
N.A.
40
P-Site Similarity:
100
100
100
33.3
N.A.
20
20
N.A.
6.6
53.3
46.6
13.3
N.A.
6.6
73.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
0
43
29
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
36
0
0
0
0
0
8
0
0
8
0
0
8
% D
% Glu:
8
8
0
0
0
8
0
0
0
0
8
8
8
0
36
% E
% Phe:
0
8
0
8
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
15
0
0
8
0
0
8
8
0
0
36
0
% G
% His:
15
0
0
8
8
0
8
0
0
0
0
0
8
8
0
% H
% Ile:
0
0
0
0
0
15
15
0
0
15
8
0
8
8
8
% I
% Lys:
0
36
8
0
8
0
0
0
0
0
0
0
29
22
0
% K
% Leu:
0
8
0
29
29
0
29
29
0
0
22
22
0
0
0
% L
% Met:
0
0
0
29
0
0
8
0
0
36
22
8
8
0
0
% M
% Asn:
8
0
22
15
0
8
0
0
50
29
8
0
0
0
8
% N
% Pro:
36
22
8
0
0
0
0
0
8
0
22
22
15
0
29
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
8
0
8
0
0
0
8
0
% R
% Ser:
8
8
8
0
8
8
0
43
29
8
0
0
0
8
8
% S
% Thr:
8
0
8
0
43
15
8
0
8
0
8
15
15
15
8
% T
% Val:
0
0
0
0
8
8
0
0
0
0
0
15
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _