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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANPEP
All Species:
20.61
Human Site:
S341
Identified Species:
34.87
UniProt:
P15144
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15144
NP_001141.2
967
109540
S341
T
P
Y
P
L
P
K
S
D
Q
I
G
L
P
D
Chimpanzee
Pan troglodytes
XP_523153
967
109577
S341
T
P
Y
P
L
P
K
S
D
Q
I
G
L
P
D
Rhesus Macaque
Macaca mulatta
XP_001093727
968
109887
S342
T
P
Y
P
L
P
K
S
D
Q
I
G
L
P
D
Dog
Lupus familis
XP_859826
931
105294
P333
E
S
A
L
L
Y
D
P
Q
S
S
S
I
G
N
Cat
Felis silvestris
Mouse
Mus musculus
P97449
966
109633
S340
T
S
Y
P
L
P
K
S
D
Q
I
A
L
P
D
Rat
Rattus norvegicus
P15684
965
109430
S340
T
A
Y
P
L
E
K
S
D
Q
I
A
L
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514698
839
94749
H241
T
F
D
I
S
I
V
H
Y
S
N
H
T
A
L
Chicken
Gallus gallus
NP_990192
967
108652
D340
A
Y
P
L
P
K
S
D
Q
V
G
L
P
D
F
Frog
Xenopus laevis
NP_001088591
963
109575
L341
P
K
S
D
Q
V
A
L
P
D
F
S
A
G
A
Zebra Danio
Brachydanio rerio
XP_001340256
965
110120
S340
S
S
Y
P
L
P
K
S
D
Q
I
A
L
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651674
999
115252
I369
V
T
F
P
L
P
K
I
D
M
I
A
L
P
E
Honey Bee
Apis mellifera
XP_396261
982
112493
L354
P
K
M
D
S
V
A
L
P
D
F
S
A
G
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783617
1060
120846
A430
L
S
K
Q
D
M
I
A
V
P
D
F
S
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37898
856
97644
H259
K
M
D
M
V
A
V
H
E
F
S
A
G
A
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
95.3
75.4
N.A.
76.3
77.8
N.A.
60.5
66.1
59
60.3
N.A.
35.6
37.2
N.A.
38.2
Protein Similarity:
100
99.4
97.9
85.1
N.A.
87.1
88.1
N.A.
70.4
78.8
74.2
74.9
N.A.
55.2
58.6
N.A.
57
P-Site Identity:
100
100
100
6.6
N.A.
86.6
80
N.A.
6.6
0
0
80
N.A.
53.3
0
N.A.
0
P-Site Similarity:
100
100
100
20
N.A.
86.6
80
N.A.
6.6
0
0
86.6
N.A.
66.6
0
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
8
15
8
0
0
0
36
15
22
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
15
8
0
8
8
50
15
8
0
0
8
43
% D
% Glu:
8
0
0
0
0
8
0
0
8
0
0
0
0
0
8
% E
% Phe:
0
8
8
0
0
0
0
0
0
8
15
8
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
22
8
22
8
% G
% His:
0
0
0
0
0
0
0
15
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
8
0
8
8
8
0
0
50
0
8
0
0
% I
% Lys:
8
15
8
0
0
8
50
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
15
58
0
0
15
0
0
0
8
50
0
8
% L
% Met:
0
8
8
8
0
8
0
0
0
8
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% N
% Pro:
15
22
8
50
8
43
0
8
15
8
0
0
8
50
0
% P
% Gln:
0
0
0
8
8
0
0
0
15
43
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
29
8
0
15
0
8
43
0
15
15
22
8
0
0
% S
% Thr:
43
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
8
0
0
0
8
15
15
0
8
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
43
0
0
8
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _