KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANPEP
All Species:
22.73
Human Site:
S377
Identified Species:
38.46
UniProt:
P15144
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15144
NP_001141.2
967
109540
S377
D
P
L
S
S
S
S
S
N
K
E
R
V
V
T
Chimpanzee
Pan troglodytes
XP_523153
967
109577
S377
D
P
L
S
S
S
S
S
N
K
E
R
V
V
T
Rhesus Macaque
Macaca mulatta
XP_001093727
968
109887
S378
D
P
L
S
S
S
S
S
N
K
E
R
V
V
T
Dog
Lupus familis
XP_859826
931
105294
E364
F
G
N
L
V
T
L
E
W
W
N
D
L
W
L
Cat
Felis silvestris
Mouse
Mus musculus
P97449
966
109633
S376
D
S
Q
S
S
S
I
S
N
K
E
R
V
V
T
Rat
Rattus norvegicus
P15684
965
109430
S376
D
P
Q
S
S
S
I
S
N
K
E
R
V
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514698
839
94749
P272
L
T
H
F
N
T
T
P
K
M
S
T
Y
L
L
Chicken
Gallus gallus
NP_990192
967
108652
G375
D
N
A
Y
S
S
I
G
N
K
E
R
V
V
T
Frog
Xenopus laevis
NP_001088591
963
109575
G372
D
E
N
V
S
S
I
G
N
K
E
R
V
V
T
Zebra Danio
Brachydanio rerio
XP_001340256
965
110120
G376
D
E
E
M
S
S
N
G
N
K
E
R
V
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651674
999
115252
N405
D
P
G
V
A
T
A
N
N
K
Q
R
V
A
S
Honey Bee
Apis mellifera
XP_396261
982
112493
S385
Q
E
G
V
S
T
S
S
N
Q
Q
R
V
A
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783617
1060
120846
S462
D
S
R
V
N
S
A
S
N
K
Q
R
V
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37898
856
97644
R290
I
E
N
S
S
L
D
R
I
Q
R
V
A
E
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
95.3
75.4
N.A.
76.3
77.8
N.A.
60.5
66.1
59
60.3
N.A.
35.6
37.2
N.A.
38.2
Protein Similarity:
100
99.4
97.9
85.1
N.A.
87.1
88.1
N.A.
70.4
78.8
74.2
74.9
N.A.
55.2
58.6
N.A.
57
P-Site Identity:
100
100
100
0
N.A.
80
86.6
N.A.
0
66.6
66.6
66.6
N.A.
40
46.6
N.A.
46.6
P-Site Similarity:
100
100
100
13.3
N.A.
80
86.6
N.A.
26.6
66.6
66.6
73.3
N.A.
80
66.6
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
15
0
0
0
0
0
8
22
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
72
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% D
% Glu:
0
29
8
0
0
0
0
8
0
0
58
0
0
8
0
% E
% Phe:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
15
0
0
0
0
22
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
29
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
72
0
0
0
0
0
% K
% Leu:
8
0
22
8
0
8
8
0
0
0
0
0
8
8
15
% L
% Met:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
8
22
0
15
0
8
8
79
0
8
0
0
0
0
% N
% Pro:
0
36
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
8
0
15
0
0
0
0
0
0
15
22
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
8
0
0
8
79
0
0
0
% R
% Ser:
0
15
0
43
72
65
29
50
0
0
8
0
0
0
8
% S
% Thr:
0
8
0
0
0
29
8
0
0
0
0
8
0
0
65
% T
% Val:
0
0
0
29
8
0
0
0
0
0
0
8
79
58
15
% V
% Trp:
0
0
0
0
0
0
0
0
8
8
0
0
0
8
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _