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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANPEP
All Species:
22.12
Human Site:
S476
Identified Species:
37.44
UniProt:
P15144
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15144
NP_001141.2
967
109540
S476
S
E
L
F
D
A
I
S
Y
S
K
G
A
S
V
Chimpanzee
Pan troglodytes
XP_523153
967
109577
S476
S
E
L
F
D
A
I
S
Y
S
K
G
A
S
V
Rhesus Macaque
Macaca mulatta
XP_001093727
968
109887
S477
S
E
L
F
D
S
I
S
Y
S
K
G
A
S
V
Dog
Lupus familis
XP_859826
931
105294
V462
E
D
L
F
K
K
G
V
A
S
Y
L
H
T
F
Cat
Felis silvestris
Mouse
Mus musculus
P97449
966
109633
T475
M
E
L
F
D
S
I
T
Y
S
K
G
A
S
V
Rat
Rattus norvegicus
P15684
965
109430
T475
S
E
L
F
D
S
I
T
Y
S
K
G
A
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514698
839
94749
P370
E
S
A
L
L
Y
D
P
L
T
S
S
S
S
N
Chicken
Gallus gallus
NP_990192
967
108652
A474
S
E
V
F
D
S
I
A
Y
S
K
G
A
S
V
Frog
Xenopus laevis
NP_001088591
963
109575
A471
S
A
L
F
D
S
I
A
Y
S
K
G
A
S
V
Zebra Danio
Brachydanio rerio
XP_001340256
965
110120
S475
S
E
V
F
D
T
I
S
Y
S
K
G
A
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651674
999
115252
K504
F
D
R
I
S
Y
A
K
G
S
T
I
I
R
M
Honey Bee
Apis mellifera
XP_396261
982
112493
K484
F
D
R
I
S
Y
E
K
G
A
S
I
I
R
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783617
1060
120846
K561
F
D
S
I
S
Y
S
K
G
A
S
I
I
R
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37898
856
97644
K388
F
D
A
I
S
Y
S
K
G
S
S
L
L
R
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
95.3
75.4
N.A.
76.3
77.8
N.A.
60.5
66.1
59
60.3
N.A.
35.6
37.2
N.A.
38.2
Protein Similarity:
100
99.4
97.9
85.1
N.A.
87.1
88.1
N.A.
70.4
78.8
74.2
74.9
N.A.
55.2
58.6
N.A.
57
P-Site Identity:
100
100
93.3
20
N.A.
80
86.6
N.A.
6.6
80
80
86.6
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
100
33.3
N.A.
93.3
100
N.A.
20
100
93.3
93.3
N.A.
20
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
0
0
15
8
15
8
15
0
0
58
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
36
0
0
58
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
15
50
0
0
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
29
0
0
65
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
8
0
29
0
0
58
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
29
0
0
58
0
0
0
0
22
22
0
0
% I
% Lys:
0
0
0
0
8
8
0
29
0
0
58
0
0
0
0
% K
% Leu:
0
0
50
8
8
0
0
0
8
0
0
15
8
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
29
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
15
0
0
0
0
0
0
0
0
0
0
29
0
% R
% Ser:
50
8
8
0
29
36
15
29
0
79
29
8
8
65
0
% S
% Thr:
0
0
0
0
0
8
0
15
0
8
8
0
0
8
0
% T
% Val:
0
0
15
0
0
0
0
8
0
0
0
0
0
0
58
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
36
0
0
58
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _