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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANPEP
All Species:
23.94
Human Site:
S762
Identified Species:
40.51
UniProt:
P15144
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15144
NP_001141.2
967
109540
S762
N
A
I
S
T
A
C
S
N
G
V
P
E
C
E
Chimpanzee
Pan troglodytes
XP_523153
967
109577
S762
N
A
I
S
T
A
C
S
N
G
V
P
E
C
E
Rhesus Macaque
Macaca mulatta
XP_001093727
968
109887
S763
N
A
I
S
T
A
C
S
N
G
V
P
E
C
E
Dog
Lupus familis
XP_859826
931
105294
R744
S
T
L
F
A
E
W
R
K
N
P
Q
N
N
P
Cat
Felis silvestris
Mouse
Mus musculus
P97449
966
109633
S761
N
A
I
S
T
A
C
S
S
G
L
K
E
C
R
Rat
Rattus norvegicus
P15684
965
109430
S761
N
A
I
S
T
A
C
S
S
G
L
E
E
C
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514698
839
94749
I653
S
H
Q
V
I
P
V
I
N
R
A
Q
I
I
S
Chicken
Gallus gallus
NP_990192
967
108652
S760
N
A
I
S
T
A
C
S
Y
G
I
A
E
C
Q
Frog
Xenopus laevis
NP_001088591
963
109575
S757
N
T
L
S
T
A
C
S
Y
D
V
E
E
C
L
Zebra Danio
Brachydanio rerio
XP_001340256
965
110120
I760
A
L
R
V
A
C
S
I
G
L
K
N
C
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651674
999
115252
G796
L
S
M
A
C
H
L
G
H
Q
E
C
I
A
E
Honey Bee
Apis mellifera
XP_396261
982
112493
E778
W
A
C
N
F
G
H
E
D
C
V
Q
N
A
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783617
1060
120846
N846
G
T
S
C
R
Y
R
N
Q
A
C
L
D
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37898
856
97644
E670
I
A
V
E
M
F
E
E
Y
A
N
G
N
K
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
95.3
75.4
N.A.
76.3
77.8
N.A.
60.5
66.1
59
60.3
N.A.
35.6
37.2
N.A.
38.2
Protein Similarity:
100
99.4
97.9
85.1
N.A.
87.1
88.1
N.A.
70.4
78.8
74.2
74.9
N.A.
55.2
58.6
N.A.
57
P-Site Identity:
100
100
100
0
N.A.
73.3
73.3
N.A.
6.6
73.3
60
0
N.A.
6.6
13.3
N.A.
0
P-Site Similarity:
100
100
100
13.3
N.A.
86.6
86.6
N.A.
13.3
86.6
66.6
6.6
N.A.
33.3
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
58
0
8
15
50
0
0
0
15
8
8
0
15
8
% A
% Cys:
0
0
8
8
8
8
50
0
0
8
8
8
8
50
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
8
0
0
8
0
8
% D
% Glu:
0
0
0
8
0
8
8
15
0
0
8
15
50
0
29
% E
% Phe:
0
0
0
8
8
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
8
0
8
8
43
0
8
0
0
0
% G
% His:
0
8
0
0
0
8
8
0
8
0
0
0
0
0
0
% H
% Ile:
8
0
43
0
8
0
0
15
0
0
8
0
15
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
8
8
0
8
0
% K
% Leu:
8
8
15
0
0
0
8
0
0
8
15
8
0
0
8
% L
% Met:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
50
0
0
8
0
0
0
8
29
8
8
8
22
8
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
8
22
0
0
8
% P
% Gln:
0
0
8
0
0
0
0
0
8
8
0
22
0
8
15
% Q
% Arg:
0
0
8
0
8
0
8
8
0
8
0
0
0
0
15
% R
% Ser:
15
8
8
50
0
0
8
50
15
0
0
0
0
0
8
% S
% Thr:
0
22
0
0
50
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
8
15
0
0
8
0
0
0
36
0
0
0
8
% V
% Trp:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
22
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _