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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANPEP
All Species:
20.61
Human Site:
T108
Identified Species:
34.87
UniProt:
P15144
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15144
NP_001141.2
967
109540
T108
Y
V
F
K
G
S
S
T
V
R
F
T
C
K
E
Chimpanzee
Pan troglodytes
XP_523153
967
109577
T108
Y
V
F
K
G
S
S
T
V
R
F
T
C
K
E
Rhesus Macaque
Macaca mulatta
XP_001093727
968
109887
T109
Y
I
F
K
G
S
S
T
V
R
F
T
C
K
E
Dog
Lupus familis
XP_859826
931
105294
P101
T
L
R
P
Y
L
T
P
N
S
N
G
L
Y
T
Cat
Felis silvestris
Mouse
Mus musculus
P97449
966
109633
T108
Y
I
F
Q
G
N
S
T
V
R
F
T
C
N
Q
Rat
Rattus norvegicus
P15684
965
109430
T108
Y
I
F
K
G
S
S
T
V
R
F
T
C
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514698
839
94749
K9
A
S
G
F
F
V
S
K
T
L
G
F
V
T
I
Chicken
Gallus gallus
NP_990192
967
108652
V108
I
F
K
G
N
S
S
V
V
F
L
C
E
E
A
Frog
Xenopus laevis
NP_001088591
963
109575
A108
V
F
H
G
K
S
S
A
F
F
L
C
N
T
A
Zebra Danio
Brachydanio rerio
XP_001340256
965
110120
G108
E
G
L
Y
I
F
T
G
E
S
S
V
V
F
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651674
999
115252
S132
I
T
I
E
P
Q
L
S
G
N
F
T
F
A
G
Honey Bee
Apis mellifera
XP_396261
982
112493
L121
F
N
G
E
V
K
I
L
V
N
V
T
E
E
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783617
1060
120846
T197
N
T
D
D
R
V
F
T
F
D
G
K
V
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37898
856
97644
T27
E
P
N
F
R
A
F
T
F
E
G
S
L
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
95.3
75.4
N.A.
76.3
77.8
N.A.
60.5
66.1
59
60.3
N.A.
35.6
37.2
N.A.
38.2
Protein Similarity:
100
99.4
97.9
85.1
N.A.
87.1
88.1
N.A.
70.4
78.8
74.2
74.9
N.A.
55.2
58.6
N.A.
57
P-Site Identity:
100
100
93.3
0
N.A.
66.6
86.6
N.A.
6.6
20
13.3
0
N.A.
13.3
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
13.3
N.A.
93.3
93.3
N.A.
6.6
26.6
13.3
6.6
N.A.
26.6
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
8
0
0
0
0
0
8
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
15
36
0
0
% C
% Asp:
0
0
8
8
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
15
0
0
15
0
0
0
0
8
8
0
0
15
15
29
% E
% Phe:
8
15
36
15
8
8
15
0
22
15
43
8
8
8
0
% F
% Gly:
0
8
15
15
36
0
0
8
8
0
22
8
0
0
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
22
8
0
8
0
8
0
0
0
0
0
0
0
22
% I
% Lys:
0
0
8
29
8
8
0
8
0
0
0
8
0
36
0
% K
% Leu:
0
8
8
0
0
8
8
8
0
8
15
0
15
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
8
0
8
8
0
0
8
15
8
0
8
15
0
% N
% Pro:
0
8
0
8
8
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
8
0
15
0
0
0
0
36
0
0
0
0
8
% R
% Ser:
0
8
0
0
0
43
58
8
0
15
8
8
0
0
0
% S
% Thr:
8
15
0
0
0
0
15
50
8
0
0
50
0
15
15
% T
% Val:
8
15
0
0
8
15
0
8
50
0
8
8
22
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
36
0
0
8
8
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _