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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANPEP
All Species:
17.88
Human Site:
T130
Identified Species:
30.26
UniProt:
P15144
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15144
NP_001141.2
967
109540
T130
H
S
K
K
L
N
Y
T
L
S
Q
G
H
R
V
Chimpanzee
Pan troglodytes
XP_523153
967
109577
T130
H
S
K
K
L
N
Y
T
L
S
Q
G
H
R
V
Rhesus Macaque
Macaca mulatta
XP_001093727
968
109887
T131
H
S
K
K
L
N
Y
T
L
S
Q
G
H
R
V
Dog
Lupus familis
XP_859826
931
105294
T123
R
F
T
C
K
E
S
T
S
M
I
I
I
H
S
Cat
Felis silvestris
Mouse
Mus musculus
P97449
966
109633
T130
H
S
K
K
L
N
Y
T
L
K
G
N
H
R
V
Rat
Rattus norvegicus
P15684
965
109430
T130
H
S
K
K
L
N
Y
T
N
K
G
N
H
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514698
839
94749
V31
A
T
I
I
A
L
S
V
V
Y
S
Q
E
K
N
Chicken
Gallus gallus
NP_990192
967
108652
L130
S
N
K
L
N
Y
T
L
Q
G
G
F
H
A
S
Frog
Xenopus laevis
NP_001088591
963
109575
K130
S
N
K
L
N
H
T
K
F
N
N
F
D
A
K
Zebra Danio
Brachydanio rerio
XP_001340256
965
110120
L130
I
L
I
H
S
N
K
L
T
I
K
D
S
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651674
999
115252
I154
V
L
E
D
C
Y
N
I
T
M
H
A
E
E
L
Honey Bee
Apis mellifera
XP_396261
982
112493
S143
V
D
M
R
I
D
E
S
F
T
N
I
K
S
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783617
1060
120846
I219
T
D
V
I
T
L
H
I
N
N
I
T
I
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37898
856
97644
N49
S
I
N
S
V
Q
I
N
Y
L
E
I
D
F
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
95.3
75.4
N.A.
76.3
77.8
N.A.
60.5
66.1
59
60.3
N.A.
35.6
37.2
N.A.
38.2
Protein Similarity:
100
99.4
97.9
85.1
N.A.
87.1
88.1
N.A.
70.4
78.8
74.2
74.9
N.A.
55.2
58.6
N.A.
57
P-Site Identity:
100
100
100
6.6
N.A.
80
73.3
N.A.
0
13.3
6.6
6.6
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
100
6.6
N.A.
80
73.3
N.A.
20
20
26.6
13.3
N.A.
13.3
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
0
0
0
0
0
8
0
15
0
% A
% Cys:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
8
0
8
0
0
0
0
0
8
15
0
0
% D
% Glu:
0
0
8
0
0
8
8
0
0
0
8
0
15
8
0
% E
% Phe:
0
8
0
0
0
0
0
0
15
0
0
15
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
22
22
0
0
0
% G
% His:
36
0
0
8
0
8
8
0
0
0
8
0
43
8
8
% H
% Ile:
8
8
15
15
8
0
8
15
0
8
15
22
15
0
0
% I
% Lys:
0
0
50
36
8
0
8
8
0
15
8
0
8
8
8
% K
% Leu:
0
15
0
15
36
15
0
15
29
8
0
0
0
0
8
% L
% Met:
0
0
8
0
0
0
0
0
0
15
0
0
0
0
0
% M
% Asn:
0
15
8
0
15
43
8
8
15
15
15
15
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
8
0
22
8
0
0
0
% Q
% Arg:
8
0
0
8
0
0
0
0
0
0
0
0
0
43
0
% R
% Ser:
22
36
0
8
8
0
15
8
8
22
8
0
8
8
22
% S
% Thr:
8
8
8
0
8
0
15
43
15
8
0
8
0
8
8
% T
% Val:
15
0
8
0
8
0
0
8
8
0
0
0
0
0
36
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
15
36
0
8
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _