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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANPEP
All Species:
23.33
Human Site:
T272
Identified Species:
39.49
UniProt:
P15144
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15144
NP_001141.2
967
109540
T272
N
V
T
E
F
H
T
T
P
K
M
S
T
Y
L
Chimpanzee
Pan troglodytes
XP_523153
967
109577
T272
S
V
T
E
F
H
T
T
P
K
M
S
T
Y
L
Rhesus Macaque
Macaca mulatta
XP_001093727
968
109887
T273
I
V
T
E
F
H
T
T
P
K
M
S
T
Y
L
Dog
Lupus familis
XP_859826
931
105294
I264
P
R
G
E
W
I
R
I
W
A
R
P
S
A
M
Cat
Felis silvestris
Mouse
Mus musculus
P97449
966
109633
T271
T
M
T
E
F
H
S
T
P
K
M
S
T
Y
L
Rat
Rattus norvegicus
P15684
965
109430
T271
N
V
T
E
F
H
P
T
P
K
M
S
T
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514698
839
94749
L172
V
V
H
L
N
E
K
L
E
A
G
K
H
Y
E
Chicken
Gallus gallus
NP_990192
967
108652
T271
N
V
T
Q
F
D
P
T
P
R
M
S
T
Y
L
Frog
Xenopus laevis
NP_001088591
963
109575
L272
T
P
K
M
S
T
Y
L
V
A
F
I
V
S
E
Zebra Danio
Brachydanio rerio
XP_001340256
965
110120
P271
L
T
K
T
T
F
A
P
T
E
K
M
S
T
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651674
999
115252
V300
H
A
T
M
P
S
Y
V
W
D
H
F
A
E
S
Honey Bee
Apis mellifera
XP_396261
982
112493
S285
V
W
D
H
Y
E
R
S
V
P
M
S
T
Y
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783617
1060
120846
K361
T
T
Y
R
A
T
P
K
M
S
T
Y
L
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37898
856
97644
M190
T
F
N
T
T
P
K
M
S
T
Y
L
V
A
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
95.3
75.4
N.A.
76.3
77.8
N.A.
60.5
66.1
59
60.3
N.A.
35.6
37.2
N.A.
38.2
Protein Similarity:
100
99.4
97.9
85.1
N.A.
87.1
88.1
N.A.
70.4
78.8
74.2
74.9
N.A.
55.2
58.6
N.A.
57
P-Site Identity:
100
93.3
93.3
6.6
N.A.
80
93.3
N.A.
13.3
73.3
0
0
N.A.
6.6
33.3
N.A.
0
P-Site Similarity:
100
100
93.3
26.6
N.A.
93.3
93.3
N.A.
13.3
86.6
0
13.3
N.A.
13.3
46.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
8
0
0
22
0
0
8
15
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
43
0
15
0
0
8
8
0
0
0
8
15
% E
% Phe:
0
8
0
0
43
8
0
0
0
0
8
8
0
0
8
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
8
0
8
8
0
36
0
0
0
0
8
0
8
0
0
% H
% Ile:
8
0
0
0
0
8
0
8
0
0
0
8
0
0
0
% I
% Lys:
0
0
15
0
0
0
15
8
0
36
8
8
0
0
0
% K
% Leu:
8
0
0
8
0
0
0
15
0
0
0
8
8
8
50
% L
% Met:
0
8
0
15
0
0
0
8
8
0
50
8
0
0
8
% M
% Asn:
22
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
0
0
8
8
22
8
43
8
0
8
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
8
0
0
15
0
0
8
8
0
0
0
0
% R
% Ser:
8
0
0
0
8
8
8
8
8
8
0
50
15
8
8
% S
% Thr:
29
15
50
15
15
15
22
43
8
8
8
0
50
8
0
% T
% Val:
15
43
0
0
0
0
0
8
15
0
0
0
15
0
0
% V
% Trp:
0
8
0
0
8
0
0
0
15
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
0
15
0
0
0
8
8
0
58
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _