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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANPEP
All Species:
23.33
Human Site:
Y176
Identified Species:
39.49
UniProt:
P15144
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15144
NP_001141.2
967
109540
Y176
S
L
V
K
D
S
Q
Y
E
M
D
S
E
F
E
Chimpanzee
Pan troglodytes
XP_523153
967
109577
Y176
S
L
V
K
D
S
Q
Y
E
M
D
S
E
F
E
Rhesus Macaque
Macaca mulatta
XP_001093727
968
109887
Y177
S
L
V
K
D
S
Q
Y
E
M
D
S
E
F
Q
Dog
Lupus familis
XP_859826
931
105294
V169
V
E
V
T
E
Y
L
V
V
H
L
R
E
P
L
Cat
Felis silvestris
Mouse
Mus musculus
P97449
966
109633
Y176
S
L
V
E
G
R
Q
Y
E
M
D
S
Q
F
Q
Rat
Rattus norvegicus
P15684
965
109430
Y176
S
L
V
K
G
H
Q
Y
E
M
D
S
E
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514698
839
94749
L77
L
P
W
N
Q
Y
R
L
P
K
S
L
I
P
D
Chicken
Gallus gallus
NP_990192
967
108652
R176
L
Q
Q
G
Q
H
Y
R
L
F
S
I
F
T
G
Frog
Xenopus laevis
NP_001088591
963
109575
Y176
A
G
K
E
Y
S
L
Y
T
E
F
I
G
E
L
Zebra Danio
Brachydanio rerio
XP_001340256
965
110120
E176
L
T
A
G
E
S
Y
E
L
Y
T
E
F
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651674
999
115252
I200
G
A
K
Q
F
F
V
I
E
L
Y
D
K
L
L
Honey Bee
Apis mellifera
XP_396261
982
112493
Y189
T
L
R
K
G
A
Q
Y
I
V
N
L
K
F
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783617
1060
120846
Y265
M
L
E
A
G
T
G
Y
V
L
E
I
E
Y
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37898
856
97644
L95
N
L
G
P
S
A
K
L
E
I
I
F
S
G
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
95.3
75.4
N.A.
76.3
77.8
N.A.
60.5
66.1
59
60.3
N.A.
35.6
37.2
N.A.
38.2
Protein Similarity:
100
99.4
97.9
85.1
N.A.
87.1
88.1
N.A.
70.4
78.8
74.2
74.9
N.A.
55.2
58.6
N.A.
57
P-Site Identity:
100
100
93.3
13.3
N.A.
66.6
80
N.A.
0
0
13.3
6.6
N.A.
6.6
33.3
N.A.
20
P-Site Similarity:
100
100
100
20
N.A.
86.6
86.6
N.A.
13.3
0
26.6
13.3
N.A.
26.6
66.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
8
0
15
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
22
0
0
0
0
0
36
8
0
0
8
% D
% Glu:
0
8
8
15
15
0
0
8
50
8
8
8
43
8
15
% E
% Phe:
0
0
0
0
8
8
0
0
0
8
8
8
15
43
0
% F
% Gly:
8
8
8
15
29
0
8
0
0
0
0
0
8
8
15
% G
% His:
0
0
0
0
0
15
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
8
8
8
22
8
0
8
% I
% Lys:
0
0
15
36
0
0
8
0
0
8
0
0
15
0
0
% K
% Leu:
22
58
0
0
0
0
15
15
15
15
8
15
0
8
29
% L
% Met:
8
0
0
0
0
0
0
0
0
36
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
8
0
8
0
0
0
0
8
0
0
0
0
15
0
% P
% Gln:
0
8
8
8
15
0
43
0
0
0
0
0
8
0
22
% Q
% Arg:
0
0
8
0
0
8
8
8
0
0
0
8
0
0
0
% R
% Ser:
36
0
0
0
8
36
0
0
0
0
15
36
8
0
0
% S
% Thr:
8
8
0
8
0
8
0
0
8
0
8
0
0
8
0
% T
% Val:
8
0
43
0
0
0
8
8
15
8
0
0
0
8
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
15
15
58
0
8
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _