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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANPEP
All Species:
21.21
Human Site:
Y332
Identified Species:
35.9
UniProt:
P15144
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15144
NP_001141.2
967
109540
Y332
L
N
F
F
A
G
H
Y
D
T
P
Y
P
L
P
Chimpanzee
Pan troglodytes
XP_523153
967
109577
Y332
L
N
F
F
A
G
H
Y
D
T
P
Y
P
L
P
Rhesus Macaque
Macaca mulatta
XP_001093727
968
109887
Y333
L
N
F
F
A
G
H
Y
D
T
P
Y
P
L
P
Dog
Lupus familis
XP_859826
931
105294
Y324
E
N
W
G
L
V
T
Y
R
E
S
A
L
L
Y
Cat
Felis silvestris
Mouse
Mus musculus
P97449
966
109633
Y331
L
N
F
F
A
Q
H
Y
N
T
S
Y
P
L
P
Rat
Rattus norvegicus
P15684
965
109430
Y331
L
N
F
F
A
Q
H
Y
N
T
A
Y
P
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514698
839
94749
K232
C
F
D
E
P
A
M
K
A
T
F
D
I
S
I
Chicken
Gallus gallus
NP_990192
967
108652
N331
S
F
F
E
R
H
Y
N
T
A
Y
P
L
P
K
Frog
Xenopus laevis
NP_001088591
963
109575
P332
K
Y
Y
R
T
P
Y
P
L
P
K
S
D
Q
V
Zebra Danio
Brachydanio rerio
XP_001340256
965
110120
Y331
L
R
F
F
E
E
Y
Y
N
S
S
Y
P
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651674
999
115252
F360
L
T
F
L
Q
D
F
F
N
V
T
F
P
L
P
Honey Bee
Apis mellifera
XP_396261
982
112493
P345
D
Y
F
K
I
K
F
P
L
P
K
M
D
S
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783617
1060
120846
F421
E
E
Y
F
D
T
P
F
P
L
S
K
Q
D
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37898
856
97644
L250
T
F
N
I
E
Y
P
L
P
K
M
D
M
V
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
95.3
75.4
N.A.
76.3
77.8
N.A.
60.5
66.1
59
60.3
N.A.
35.6
37.2
N.A.
38.2
Protein Similarity:
100
99.4
97.9
85.1
N.A.
87.1
88.1
N.A.
70.4
78.8
74.2
74.9
N.A.
55.2
58.6
N.A.
57
P-Site Identity:
100
100
100
20
N.A.
80
73.3
N.A.
6.6
6.6
0
53.3
N.A.
33.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
86.6
80
N.A.
6.6
13.3
13.3
73.3
N.A.
53.3
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
36
8
0
0
8
8
8
8
0
0
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
8
8
0
0
22
0
0
15
15
8
0
% D
% Glu:
15
8
0
15
15
8
0
0
0
8
0
0
0
0
8
% E
% Phe:
0
22
65
50
0
0
15
15
0
0
8
8
0
0
0
% F
% Gly:
0
0
0
8
0
22
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
36
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
8
0
0
0
0
0
0
0
8
0
8
% I
% Lys:
8
0
0
8
0
8
0
8
0
8
15
8
0
0
8
% K
% Leu:
50
0
0
8
8
0
0
8
15
8
0
0
15
58
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
8
8
8
0
8
% M
% Asn:
0
43
8
0
0
0
0
8
29
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
8
15
15
15
15
22
8
50
8
43
% P
% Gln:
0
0
0
0
8
15
0
0
0
0
0
0
8
8
0
% Q
% Arg:
0
8
0
8
8
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
0
0
0
0
8
29
8
0
15
0
% S
% Thr:
8
8
0
0
8
8
8
0
8
43
8
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
8
0
0
0
8
15
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
15
0
0
8
22
50
0
0
8
43
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _