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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANPEP
All Species:
25.76
Human Site:
Y424
Identified Species:
43.59
UniProt:
P15144
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15144
NP_001141.2
967
109540
Y424
V
E
Y
L
G
A
D
Y
A
E
P
T
W
N
L
Chimpanzee
Pan troglodytes
XP_523153
967
109577
Y424
V
E
Y
L
G
A
D
Y
A
E
P
T
W
N
L
Rhesus Macaque
Macaca mulatta
XP_001093727
968
109887
Y425
V
E
Y
L
G
A
D
Y
A
E
P
T
W
N
L
Dog
Lupus familis
XP_859826
931
105294
A410
Y
R
V
M
A
V
D
A
L
A
S
S
H
P
L
Cat
Felis silvestris
Mouse
Mus musculus
P97449
966
109633
Y423
V
E
Y
L
G
A
D
Y
A
E
P
T
W
N
L
Rat
Rattus norvegicus
P15684
965
109430
Y423
V
E
F
L
G
A
D
Y
A
E
P
T
W
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514698
839
94749
N318
G
H
G
D
Y
A
L
N
K
T
G
P
I
L
K
Chicken
Gallus gallus
NP_990192
967
108652
S422
V
E
Y
L
G
A
D
S
A
E
P
T
W
D
I
Frog
Xenopus laevis
NP_001088591
963
109575
E419
V
E
Y
L
G
A
D
E
A
E
P
D
W
N
I
Zebra Danio
Brachydanio rerio
XP_001340256
965
110120
K423
V
E
Y
L
G
A
D
K
A
E
P
L
W
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651674
999
115252
A452
M
E
Y
L
T
A
D
A
V
A
P
E
W
K
Q
Honey Bee
Apis mellifera
XP_396261
982
112493
A432
M
E
Y
I
G
M
N
A
V
E
P
T
W
K
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783617
1060
120846
Y509
V
E
Y
L
G
V
D
Y
T
E
P
D
W
G
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37898
856
97644
K336
M
S
W
Y
S
C
N
K
F
Q
P
E
W
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
95.3
75.4
N.A.
76.3
77.8
N.A.
60.5
66.1
59
60.3
N.A.
35.6
37.2
N.A.
38.2
Protein Similarity:
100
99.4
97.9
85.1
N.A.
87.1
88.1
N.A.
70.4
78.8
74.2
74.9
N.A.
55.2
58.6
N.A.
57
P-Site Identity:
100
100
100
13.3
N.A.
100
93.3
N.A.
6.6
80
80
80
N.A.
46.6
46.6
N.A.
66.6
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
6.6
93.3
86.6
86.6
N.A.
53.3
73.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
72
0
22
58
15
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
79
0
0
0
0
15
0
8
0
% D
% Glu:
0
79
0
0
0
0
0
8
0
72
0
15
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
72
0
0
0
0
0
8
0
0
8
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
22
% I
% Lys:
0
0
0
0
0
0
0
15
8
0
0
0
0
22
8
% K
% Leu:
0
0
0
72
0
0
8
0
8
0
0
8
0
8
43
% L
% Met:
22
0
0
8
0
8
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
15
8
0
0
0
0
0
50
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
86
8
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
8
0
0
8
0
0
8
8
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
0
8
8
0
50
0
0
0
% T
% Val:
65
0
8
0
0
15
0
0
15
0
0
0
0
0
15
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
86
0
0
% W
% Tyr:
8
0
72
8
8
0
0
43
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _