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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANPEP
All Species:
27.88
Human Site:
Y514
Identified Species:
47.18
UniProt:
P15144
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15144
NP_001141.2
967
109540
Y514
F
A
Y
Q
N
T
I
Y
L
N
L
W
D
H
L
Chimpanzee
Pan troglodytes
XP_523153
967
109577
Y514
F
A
Y
Q
N
T
I
Y
L
N
L
W
D
H
L
Rhesus Macaque
Macaca mulatta
XP_001093727
968
109887
Y515
F
A
Y
Q
N
T
I
Y
L
N
L
W
D
H
L
Dog
Lupus familis
XP_859826
931
105294
N500
I
N
L
P
Y
T
V
N
A
I
M
D
R
W
I
Cat
Felis silvestris
Mouse
Mus musculus
P97449
966
109633
Y513
Y
Q
Y
S
N
T
V
Y
L
D
L
W
E
H
L
Rat
Rattus norvegicus
P15684
965
109430
Y513
F
Q
Y
S
N
T
I
Y
L
D
L
W
E
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514698
839
94749
L408
A
W
W
N
D
L
W
L
N
E
G
F
A
S
Y
Chicken
Gallus gallus
NP_990192
967
108652
Y512
F
S
Y
N
N
T
V
Y
T
D
L
W
D
H
L
Frog
Xenopus laevis
NP_001088591
963
109575
Y509
F
E
Y
D
N
T
V
Y
S
D
L
W
T
H
L
Zebra Danio
Brachydanio rerio
XP_001340256
965
110120
Y513
F
K
F
N
N
T
V
Y
T
D
L
W
D
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651674
999
115252
L542
N
S
A
T
Q
D
D
L
W
H
F
L
T
V
E
Honey Bee
Apis mellifera
XP_396261
982
112493
L522
Q
S
A
E
Q
N
D
L
W
D
A
L
T
K
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783617
1060
120846
L599
G
N
A
D
S
D
D
L
W
F
A
L
K
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37898
856
97644
L426
G
N
A
K
T
G
D
L
W
D
A
L
A
D
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
95.3
75.4
N.A.
76.3
77.8
N.A.
60.5
66.1
59
60.3
N.A.
35.6
37.2
N.A.
38.2
Protein Similarity:
100
99.4
97.9
85.1
N.A.
87.1
88.1
N.A.
70.4
78.8
74.2
74.9
N.A.
55.2
58.6
N.A.
57
P-Site Identity:
100
100
100
6.6
N.A.
60
73.3
N.A.
0
66.6
60
60
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
100
26.6
N.A.
86.6
86.6
N.A.
20
86.6
73.3
80
N.A.
13.3
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
22
29
0
0
0
0
0
8
0
22
0
15
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
15
8
15
29
0
0
50
0
8
36
8
0
% D
% Glu:
0
8
0
8
0
0
0
0
0
8
0
0
15
8
8
% E
% Phe:
50
0
8
0
0
0
0
0
0
8
8
8
0
0
0
% F
% Gly:
15
0
0
0
0
8
0
0
0
0
8
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
58
0
% H
% Ile:
8
0
0
0
0
0
29
0
0
8
0
0
0
0
8
% I
% Lys:
0
8
0
8
0
0
0
0
0
0
0
0
8
8
0
% K
% Leu:
0
0
8
0
0
8
0
36
36
0
58
29
0
0
58
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
22
0
22
58
8
0
8
8
22
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
15
0
22
15
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
22
0
15
8
0
0
0
8
0
0
0
0
8
0
% S
% Thr:
0
0
0
8
8
65
0
0
15
0
0
0
22
0
0
% T
% Val:
0
0
0
0
0
0
36
0
0
0
0
0
0
8
0
% V
% Trp:
0
8
8
0
0
0
8
0
29
0
0
58
0
8
0
% W
% Tyr:
8
0
50
0
8
0
0
58
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _