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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANPEP
All Species:
14.85
Human Site:
Y582
Identified Species:
25.13
UniProt:
P15144
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15144
NP_001141.2
967
109540
Y582
T
R
P
S
E
F
N
Y
V
W
I
V
P
I
T
Chimpanzee
Pan troglodytes
XP_523153
967
109577
Y582
T
R
P
S
E
F
N
Y
V
W
I
V
P
I
T
Rhesus Macaque
Macaca mulatta
XP_001093727
968
109887
Y583
T
R
P
S
E
F
N
Y
L
W
I
V
P
I
T
Dog
Lupus familis
XP_859826
931
105294
N568
A
H
Y
W
M
P
D
N
A
K
V
Q
N
D
L
Cat
Felis silvestris
Mouse
Mus musculus
P97449
966
109633
N581
V
T
R
P
S
E
F
N
Y
I
W
I
A
P
I
Rat
Rattus norvegicus
P15684
965
109430
N581
P
T
R
P
S
D
F
N
Y
L
W
I
V
P
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514698
839
94749
Y476
E
L
F
D
S
I
S
Y
S
K
G
A
S
V
L
Chicken
Gallus gallus
NP_990192
967
108652
Y580
E
R
P
S
V
F
N
Y
T
W
I
V
P
I
T
Frog
Xenopus laevis
NP_001088591
963
109575
D577
V
T
R
P
S
P
F
D
Y
K
W
I
V
P
I
Zebra Danio
Brachydanio rerio
XP_001340256
965
110120
E581
E
P
S
E
F
N
Y
E
W
F
V
P
I
T
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651674
999
115252
W610
R
E
D
E
S
L
L
W
Y
I
P
I
T
F
T
Honey Bee
Apis mellifera
XP_396261
982
112493
E590
M
V
T
T
S
N
V
E
P
L
W
W
I
P
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783617
1060
120846
T667
Y
L
W
Y
V
Y
L
T
Y
T
Q
A
T
N
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37898
856
97644
S494
I
L
L
A
L
K
D
S
T
G
I
D
N
T
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
95.3
75.4
N.A.
76.3
77.8
N.A.
60.5
66.1
59
60.3
N.A.
35.6
37.2
N.A.
38.2
Protein Similarity:
100
99.4
97.9
85.1
N.A.
87.1
88.1
N.A.
70.4
78.8
74.2
74.9
N.A.
55.2
58.6
N.A.
57
P-Site Identity:
100
100
93.3
0
N.A.
0
0
N.A.
6.6
80
0
0
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
100
13.3
N.A.
6.6
6.6
N.A.
20
80
6.6
13.3
N.A.
20
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
0
8
0
0
15
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
8
15
8
0
0
0
8
0
8
0
% D
% Glu:
22
8
0
15
22
8
0
15
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
8
29
22
0
0
8
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
8
0
0
0
15
36
29
15
29
29
% I
% Lys:
0
0
0
0
0
8
0
0
0
22
0
0
0
0
0
% K
% Leu:
0
22
8
0
8
8
15
0
8
15
0
0
0
0
22
% L
% Met:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
15
29
22
0
0
0
0
15
8
0
% N
% Pro:
8
8
29
22
0
15
0
0
8
0
8
8
29
29
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% Q
% Arg:
8
29
22
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
29
43
0
8
8
8
0
0
0
8
0
0
% S
% Thr:
22
22
8
8
0
0
0
8
15
8
0
0
15
15
36
% T
% Val:
15
8
0
0
15
0
8
0
15
0
15
29
15
8
0
% V
% Trp:
0
0
8
8
0
0
0
8
8
29
29
8
0
0
8
% W
% Tyr:
8
0
8
8
0
8
8
36
36
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _