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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANPEP
All Species:
20
Human Site:
Y85
Identified Species:
33.85
UniProt:
P15144
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15144
NP_001141.2
967
109540
Y85
N
T
L
K
P
D
S
Y
R
V
T
L
R
P
Y
Chimpanzee
Pan troglodytes
XP_523153
967
109577
Y85
N
T
L
K
P
D
S
Y
Q
V
T
L
R
P
Y
Rhesus Macaque
Macaca mulatta
XP_001093727
968
109887
Y86
N
T
L
K
P
D
S
Y
Q
V
T
L
R
P
Y
Dog
Lupus familis
XP_859826
931
105294
N78
L
A
Q
S
K
P
W
N
H
Y
R
L
P
K
T
Cat
Felis silvestris
Mouse
Mus musculus
P97449
966
109633
Y85
K
T
L
I
P
D
S
Y
R
V
I
L
R
P
Y
Rat
Rattus norvegicus
P15684
965
109430
Y85
K
T
L
I
P
D
S
Y
Q
V
T
L
R
P
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514698
839
94749
Chicken
Gallus gallus
NP_990192
967
108652
E85
A
L
K
P
E
S
Y
E
V
T
L
Q
P
F
L
Frog
Xenopus laevis
NP_001088591
963
109575
D85
T
L
K
P
I
H
Y
D
V
E
L
Q
P
Y
L
Zebra Danio
Brachydanio rerio
XP_001340256
965
110120
P85
R
L
P
Q
T
L
S
P
E
T
Y
K
V
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651674
999
115252
D109
H
D
D
T
P
K
Y
D
R
D
V
R
L
P
H
Honey Bee
Apis mellifera
XP_396261
982
112493
S98
P
R
S
I
V
P
V
S
Y
E
L
R
L
V
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783617
1060
120846
Y174
R
D
V
I
P
E
N
Y
Q
L
Y
L
K
P
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37898
856
97644
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
95.3
75.4
N.A.
76.3
77.8
N.A.
60.5
66.1
59
60.3
N.A.
35.6
37.2
N.A.
38.2
Protein Similarity:
100
99.4
97.9
85.1
N.A.
87.1
88.1
N.A.
70.4
78.8
74.2
74.9
N.A.
55.2
58.6
N.A.
57
P-Site Identity:
100
93.3
93.3
6.6
N.A.
80
80
N.A.
0
0
0
6.6
N.A.
20
0
N.A.
33.3
P-Site Similarity:
100
100
100
6.6
N.A.
80
86.6
N.A.
0
0
0
13.3
N.A.
33.3
0
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
8
0
0
36
0
15
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
8
8
0
8
8
15
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
8
0
0
8
0
0
0
0
0
8
% H
% Ile:
0
0
0
29
8
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
15
0
15
22
8
8
0
0
0
0
0
8
8
8
0
% K
% Leu:
8
22
36
0
0
8
0
0
0
8
22
50
15
0
22
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
22
0
0
0
0
0
8
8
0
0
0
0
0
8
0
% N
% Pro:
8
0
8
15
50
15
0
8
0
0
0
0
22
50
8
% P
% Gln:
0
0
8
8
0
0
0
0
29
0
0
15
0
0
0
% Q
% Arg:
15
8
0
0
0
0
0
0
22
0
8
15
36
0
0
% R
% Ser:
0
0
8
8
0
8
43
8
0
0
0
0
0
0
0
% S
% Thr:
8
36
0
8
8
0
0
0
0
15
29
0
0
0
8
% T
% Val:
0
0
8
0
8
0
8
0
15
36
8
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
22
43
8
8
15
0
0
8
43
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _