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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANPEP
All Species:
31.52
Human Site:
Y891
Identified Species:
53.33
UniProt:
P15144
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15144
NP_001141.2
967
109540
Y891
W
K
K
L
F
N
D
Y
G
G
G
S
F
S
F
Chimpanzee
Pan troglodytes
XP_523153
967
109577
Y891
W
K
K
L
F
N
D
Y
G
G
G
S
F
S
F
Rhesus Macaque
Macaca mulatta
XP_001093727
968
109887
Y892
W
K
K
L
F
N
D
Y
G
G
G
S
F
S
F
Dog
Lupus familis
XP_859826
931
105294
S859
F
E
D
Y
G
T
G
S
F
S
F
S
N
L
I
Cat
Felis silvestris
Mouse
Mus musculus
P97449
966
109633
Y890
W
K
K
L
F
E
N
Y
G
G
G
S
F
S
F
Rat
Rattus norvegicus
P15684
965
109430
Y890
W
K
K
L
F
E
D
Y
G
G
G
S
F
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514698
839
94749
L768
G
V
I
E
C
Q
E
L
A
S
R
L
F
R
E
Chicken
Gallus gallus
NP_990192
967
108652
Y889
W
R
T
L
F
G
Q
Y
G
G
G
S
F
S
F
Frog
Xenopus laevis
NP_001088591
963
109575
F886
W
K
T
L
Y
S
M
F
G
E
S
S
F
S
F
Zebra Danio
Brachydanio rerio
XP_001340256
965
110120
Y888
W
E
Y
I
F
N
Q
Y
G
G
G
S
F
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651674
999
115252
M926
W
Q
E
I
K
T
Y
M
G
S
Q
M
S
S
I
Honey Bee
Apis mellifera
XP_396261
982
112493
Y906
K
W
A
R
L
R
E
Y
F
G
T
S
L
L
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783617
1060
120846
Y982
W
D
T
V
Y
D
Y
Y
G
G
S
S
F
S
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37898
856
97644
S785
A
K
R
L
Q
P
G
S
P
V
L
G
G
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
95.3
75.4
N.A.
76.3
77.8
N.A.
60.5
66.1
59
60.3
N.A.
35.6
37.2
N.A.
38.2
Protein Similarity:
100
99.4
97.9
85.1
N.A.
87.1
88.1
N.A.
70.4
78.8
74.2
74.9
N.A.
55.2
58.6
N.A.
57
P-Site Identity:
100
100
100
6.6
N.A.
86.6
93.3
N.A.
6.6
73.3
53.3
73.3
N.A.
20
20
N.A.
53.3
P-Site Similarity:
100
100
100
20
N.A.
93.3
93.3
N.A.
13.3
80
73.3
86.6
N.A.
40
26.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
8
29
0
0
0
0
0
0
0
0
% D
% Glu:
0
15
8
8
0
15
15
0
0
8
0
0
0
0
8
% E
% Phe:
8
0
0
0
50
0
0
8
15
0
8
0
72
0
65
% F
% Gly:
8
0
0
0
8
8
15
0
72
65
50
8
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
15
0
0
0
0
0
0
0
0
0
0
15
% I
% Lys:
8
50
36
0
8
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
58
8
0
0
8
0
0
8
8
8
15
8
% L
% Met:
0
0
0
0
0
0
8
8
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
29
8
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
8
8
15
0
0
0
8
0
0
0
0
% Q
% Arg:
0
8
8
8
0
8
0
0
0
0
8
0
0
8
0
% R
% Ser:
0
0
0
0
0
8
0
15
0
22
15
79
8
72
0
% S
% Thr:
0
0
22
0
0
15
0
0
0
0
8
0
0
0
8
% T
% Val:
0
8
0
8
0
0
0
0
0
8
0
0
0
8
0
% V
% Trp:
72
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
15
0
15
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _