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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PVR All Species: 15.15
Human Site: S399 Identified Species: 41.67
UniProt: P15151 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P15151 NP_001129240.1 417 45303 S399 A N G H V S Y S A V S R E N S
Chimpanzee Pan troglodytes XP_001161582 417 45294 S399 A N G H V S Y S A V S R E N S
Rhesus Macaque Macaca mulatta NP_001036851 417 45455 S399 A N G Y I S Y S D V S R E A S
Dog Lupus familis XP_533645 391 42129 T373 A N G H V I Y T A V N P D A S
Cat Felis silvestris
Mouse Mus musculus P32507 530 57299 S484 V V E G V S L S L E D E E E D
Rat Rattus norvegicus NP_001012064 530 57305 G484 V V E G V S L G L E D E E E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519017 849 91247 T489 G S P P L T G T V N L K L S G
Chicken Gallus gallus
Frog Xenopus laevis NP_001087644 463 50753 P441 Q L R P H H D P Y L D D D M E
Zebra Danio Brachydanio rerio Q58EG3 574 63977 L529 H H I Q R S S L Q P Q P R R Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 90.1 54.6 N.A. 40.3 39.6 N.A. 24.5 N.A. 32.8 24.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.3 94.4 67.6 N.A. 52.4 52.4 N.A. 34.1 N.A. 49.2 38.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 73.3 60 N.A. 26.6 20 N.A. 0 N.A. 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 80 N.A. 26.6 20 N.A. 40 N.A. 13.3 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 45 0 0 0 0 0 0 0 34 0 0 0 0 23 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 12 0 12 0 34 12 23 0 23 % D
% Glu: 0 0 23 0 0 0 0 0 0 23 0 23 56 23 12 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 12 0 45 23 0 0 12 12 0 0 0 0 0 0 12 % G
% His: 12 12 0 34 12 12 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 12 0 12 12 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % K
% Leu: 0 12 0 0 12 0 23 12 23 12 12 0 12 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % M
% Asn: 0 45 0 0 0 0 0 0 0 12 12 0 0 23 0 % N
% Pro: 0 0 12 23 0 0 0 12 0 12 0 23 0 0 0 % P
% Gln: 12 0 0 12 0 0 0 0 12 0 12 0 0 0 0 % Q
% Arg: 0 0 12 0 12 0 0 0 0 0 0 34 12 12 0 % R
% Ser: 0 12 0 0 0 67 12 45 0 0 34 0 0 12 45 % S
% Thr: 0 0 0 0 0 12 0 23 0 0 0 0 0 0 0 % T
% Val: 23 23 0 0 56 0 0 0 12 45 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 12 0 0 45 0 12 0 0 0 0 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _