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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GSPT1
All Species:
22.73
Human Site:
S16
Identified Species:
35.71
UniProt:
P15170
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15170
NP_001123479.1
499
55756
S16
E
N
G
E
T
E
M
S
P
E
E
S
W
E
H
Chimpanzee
Pan troglodytes
XP_001140542
404
45524
Rhesus Macaque
Macaca mulatta
XP_001107851
864
92841
S381
E
N
G
E
T
E
M
S
P
E
E
S
W
E
H
Dog
Lupus familis
XP_536971
499
55716
S16
E
N
G
E
T
E
M
S
P
E
E
S
W
E
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8R050
499
55692
S16
E
N
G
E
T
E
M
S
P
E
E
S
W
E
H
Rat
Rattus norvegicus
Q6AXM7
679
74756
L97
D
A
V
P
D
D
I
L
T
E
A
I
L
K
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517098
414
45834
Chicken
Gallus gallus
NP_001129149
618
67640
S135
E
N
G
E
T
E
M
S
P
E
E
S
W
E
H
Frog
Xenopus laevis
NP_001086960
553
61252
S70
E
N
G
E
T
E
M
S
P
E
E
S
W
D
H
Zebra Danio
Brachydanio rerio
NP_942101
577
63652
D93
D
A
E
M
A
T
D
D
T
W
E
Q
K
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477259
619
66434
D145
K
I
A
N
N
E
T
D
P
A
D
S
W
D
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P53013
463
50650
V16
N
I
V
V
I
G
H
V
D
S
G
K
S
T
T
Sea Urchin
Strong. purpuratus
XP_785469
575
63867
A76
T
D
A
A
Q
N
S
A
G
F
G
N
E
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P05453
685
76532
G25
Q
N
G
N
Q
Q
Q
G
N
N
R
Y
Q
G
Y
Red Bread Mold
Neurospora crassa
Q01372
460
49654
H16
I
N
V
V
V
I
G
H
V
D
S
G
K
S
T
Conservation
Percent
Protein Identity:
100
80.9
55
98.1
N.A.
98.5
32.5
N.A.
78.3
78.1
83.7
75.5
N.A.
57.5
N.A.
36
61.2
Protein Similarity:
100
80.9
56.1
98.8
N.A.
99
47.2
N.A.
81.1
78.9
87.3
80.5
N.A.
66.8
N.A.
53.3
74.2
P-Site Identity:
100
0
100
100
N.A.
100
13.3
N.A.
0
100
93.3
6.6
N.A.
26.6
N.A.
0
0
P-Site Similarity:
100
0
100
100
N.A.
100
40
N.A.
0
100
100
13.3
N.A.
46.6
N.A.
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
40.2
35.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.1
52.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
14
7
7
0
0
7
0
7
7
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
7
0
0
7
7
7
14
7
7
7
0
0
20
0
% D
% Glu:
40
0
7
40
0
47
0
0
0
47
47
0
7
34
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
0
47
0
0
7
7
7
7
0
14
7
0
14
0
% G
% His:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
47
% H
% Ile:
7
14
0
0
7
7
7
0
0
0
0
7
0
0
0
% I
% Lys:
7
0
0
0
0
0
0
0
0
0
0
7
14
7
0
% K
% Leu:
0
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% L
% Met:
0
0
0
7
0
0
40
0
0
0
0
0
0
0
0
% M
% Asn:
7
54
0
14
7
7
0
0
7
7
0
7
0
0
0
% N
% Pro:
0
0
0
7
0
0
0
0
47
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
14
7
7
0
0
0
0
7
7
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
7
40
0
7
7
47
7
7
7
% S
% Thr:
7
0
0
0
40
7
7
0
14
0
0
0
0
7
14
% T
% Val:
0
0
20
14
7
0
0
7
7
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
47
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _