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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GSPT1
All Species:
26.06
Human Site:
S62
Identified Species:
40.95
UniProt:
P15170
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15170
NP_001123479.1
499
55756
S62
E
E
I
P
K
P
K
S
V
V
A
P
P
G
A
Chimpanzee
Pan troglodytes
XP_001140542
404
45524
W26
K
E
K
N
R
E
T
W
Y
L
S
W
A
L
D
Rhesus Macaque
Macaca mulatta
XP_001107851
864
92841
S427
E
E
I
P
K
P
K
S
V
V
A
P
P
G
A
Dog
Lupus familis
XP_536971
499
55716
S62
E
E
I
P
K
P
K
S
V
V
A
P
P
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8R050
499
55692
S62
E
E
I
P
K
P
K
S
A
V
A
P
P
G
A
Rat
Rattus norvegicus
Q6AXM7
679
74756
S149
S
R
S
S
Q
S
E
S
E
I
V
P
K
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517098
414
45834
S39
G
L
E
M
R
Y
L
S
W
A
L
D
T
N
Q
Chicken
Gallus gallus
NP_001129149
618
67640
S181
E
E
M
P
K
P
K
S
V
V
A
P
P
G
A
Frog
Xenopus laevis
NP_001086960
553
61252
T116
E
E
I
P
K
P
K
T
I
V
A
P
P
D
A
Zebra Danio
Brachydanio rerio
NP_942101
577
63652
V140
E
E
V
P
T
P
K
V
V
P
T
Q
P
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477259
619
66434
S191
V
K
V
E
E
N
R
S
K
R
E
H
V
N
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P53013
463
50650
K62
K
Y
A
W
V
L
D
K
L
K
A
E
R
E
R
Sea Urchin
Strong. purpuratus
XP_785469
575
63867
A130
K
D
N
G
S
M
K
A
F
I
A
P
K
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P05453
685
76532
K142
Q
A
A
P
K
P
K
K
T
L
K
L
V
S
S
Red Bread Mold
Neurospora crassa
Q01372
460
49654
L61
S
F
K
Y
A
W
V
L
D
K
L
K
A
E
R
Conservation
Percent
Protein Identity:
100
80.9
55
98.1
N.A.
98.5
32.5
N.A.
78.3
78.1
83.7
75.5
N.A.
57.5
N.A.
36
61.2
Protein Similarity:
100
80.9
56.1
98.8
N.A.
99
47.2
N.A.
81.1
78.9
87.3
80.5
N.A.
66.8
N.A.
53.3
74.2
P-Site Identity:
100
6.6
100
100
N.A.
93.3
20
N.A.
6.6
93.3
80
53.3
N.A.
6.6
N.A.
6.6
20
P-Site Similarity:
100
33.3
100
100
N.A.
93.3
40
N.A.
13.3
100
93.3
60
N.A.
33.3
N.A.
20
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
40.2
35.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.1
52.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
14
0
7
0
0
7
7
7
54
0
14
0
54
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
7
0
7
0
0
7
0
7
7
% D
% Glu:
47
54
7
7
7
7
7
0
7
0
7
7
0
14
0
% E
% Phe:
0
7
0
0
0
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
7
0
0
7
0
0
0
0
0
0
0
0
0
34
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
34
0
0
0
0
0
7
14
0
0
0
0
0
% I
% Lys:
20
7
14
0
47
0
60
14
7
14
7
7
14
0
0
% K
% Leu:
0
7
0
0
0
7
7
7
7
14
14
7
0
7
0
% L
% Met:
0
0
7
7
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
7
0
7
0
0
0
0
0
0
0
20
0
% N
% Pro:
0
0
0
54
0
54
0
0
0
7
0
54
47
7
0
% P
% Gln:
7
0
0
0
7
0
0
0
0
0
0
7
0
0
7
% Q
% Arg:
0
7
0
0
14
0
7
0
0
7
0
0
7
0
14
% R
% Ser:
14
0
7
7
7
7
0
54
0
0
7
0
0
7
14
% S
% Thr:
0
0
0
0
7
0
7
7
7
0
7
0
7
0
0
% T
% Val:
7
0
14
0
7
0
7
7
34
40
7
0
14
7
7
% V
% Trp:
0
0
0
7
0
7
0
7
7
0
0
7
0
0
0
% W
% Tyr:
0
7
0
7
0
7
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _