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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GSPT1
All Species:
39.7
Human Site:
T120
Identified Species:
62.38
UniProt:
P15170
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15170
NP_001123479.1
499
55756
T120
A
K
E
K
N
R
E
T
W
Y
L
S
W
A
L
Chimpanzee
Pan troglodytes
XP_001140542
404
45524
N73
G
H
K
S
F
V
P
N
M
I
G
G
A
S
Q
Rhesus Macaque
Macaca mulatta
XP_001107851
864
92841
T485
A
K
E
K
N
R
E
T
W
Y
L
S
W
A
L
Dog
Lupus familis
XP_536971
499
55716
T120
A
K
E
K
N
R
E
T
W
Y
L
S
W
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R050
499
55692
T120
A
K
E
K
N
R
E
T
W
Y
L
S
W
A
L
Rat
Rattus norvegicus
Q6AXM7
679
74756
S301
S
K
K
A
G
K
A
S
F
A
Y
A
W
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517098
414
45834
G86
S
F
V
P
N
M
I
G
G
A
S
Q
A
D
L
Chicken
Gallus gallus
NP_001129149
618
67640
T239
A
K
E
K
N
R
E
T
W
Y
L
S
W
A
L
Frog
Xenopus laevis
NP_001086960
553
61252
T174
A
K
E
K
N
R
E
T
W
Y
L
S
W
A
L
Zebra Danio
Brachydanio rerio
NP_942101
577
63652
T198
A
K
E
K
N
R
E
T
W
Y
L
S
W
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477259
619
66434
S241
A
R
E
K
S
R
E
S
W
Y
L
S
W
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P53013
463
50650
A109
M
I
T
G
T
S
Q
A
D
C
A
V
L
V
V
Sea Urchin
Strong. purpuratus
XP_785469
575
63867
S199
A
K
E
K
N
R
E
S
W
Y
L
S
W
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P05453
685
76532
G306
A
K
D
A
G
R
Q
G
W
Y
L
S
W
V
M
Red Bread Mold
Neurospora crassa
Q01372
460
49654
S108
K
N
M
I
T
G
T
S
Q
A
D
C
A
I
L
Conservation
Percent
Protein Identity:
100
80.9
55
98.1
N.A.
98.5
32.5
N.A.
78.3
78.1
83.7
75.5
N.A.
57.5
N.A.
36
61.2
Protein Similarity:
100
80.9
56.1
98.8
N.A.
99
47.2
N.A.
81.1
78.9
87.3
80.5
N.A.
66.8
N.A.
53.3
74.2
P-Site Identity:
100
0
100
100
N.A.
100
20
N.A.
13.3
100
100
100
N.A.
80
N.A.
0
93.3
P-Site Similarity:
100
13.3
100
100
N.A.
100
60
N.A.
20
100
100
100
N.A.
100
N.A.
13.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
40.2
35.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.1
52.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
0
0
14
0
0
7
7
0
20
7
7
20
60
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% C
% Asp:
0
0
7
0
0
0
0
0
7
0
7
0
0
7
0
% D
% Glu:
0
0
60
0
0
0
60
0
0
0
0
0
0
0
0
% E
% Phe:
0
7
0
0
7
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
7
0
0
7
14
7
0
14
7
0
7
7
0
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
7
0
0
7
0
0
7
0
0
0
7
0
% I
% Lys:
7
67
14
60
0
7
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
67
0
7
0
80
% L
% Met:
7
0
7
0
0
7
0
0
7
0
0
0
0
0
7
% M
% Asn:
0
7
0
0
60
0
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
7
0
0
7
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
14
0
7
0
0
7
0
0
7
% Q
% Arg:
0
7
0
0
0
67
0
0
0
0
0
0
0
0
0
% R
% Ser:
14
0
0
7
7
7
0
27
0
0
7
67
0
7
0
% S
% Thr:
0
0
7
0
14
0
7
47
0
0
0
0
0
0
0
% T
% Val:
0
0
7
0
0
7
0
0
0
0
0
7
0
20
7
% V
% Trp:
0
0
0
0
0
0
0
0
67
0
0
0
74
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
67
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _