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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GSPT1
All Species:
33.03
Human Site:
T315
Identified Species:
51.9
UniProt:
P15170
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15170
NP_001123479.1
499
55756
T315
D
K
Y
K
D
M
G
T
V
V
L
G
K
L
E
Chimpanzee
Pan troglodytes
XP_001140542
404
45524
D255
V
L
G
I
L
S
D
D
V
E
T
D
T
V
A
Rhesus Macaque
Macaca mulatta
XP_001107851
864
92841
F680
D
K
Y
K
R
Q
G
F
T
V
L
A
R
M
K
Dog
Lupus familis
XP_536971
499
55716
T315
D
K
Y
K
D
M
G
T
V
V
L
G
K
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R050
499
55692
T315
D
K
Y
K
D
M
G
T
V
V
L
G
K
L
E
Rat
Rattus norvegicus
Q6AXM7
679
74756
S496
D
V
F
K
D
Q
G
S
G
F
C
V
T
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517098
414
45834
V266
L
G
I
L
S
D
D
V
E
T
E
S
V
A
P
Chicken
Gallus gallus
NP_001129149
618
67640
T434
D
K
Y
K
D
M
G
T
V
V
L
G
K
L
E
Frog
Xenopus laevis
NP_001086960
553
61252
T369
D
K
Y
K
D
M
G
T
V
I
L
G
K
L
E
Zebra Danio
Brachydanio rerio
NP_942101
577
63652
T393
D
K
Y
K
D
M
G
T
V
I
L
G
K
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477259
619
66434
T438
D
K
Y
K
D
M
G
T
V
V
M
G
K
V
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P53013
463
50650
V289
P
Q
N
V
T
T
E
V
K
S
V
E
M
H
H
Sea Urchin
Strong. purpuratus
XP_785469
575
63867
G394
T
D
R
Y
K
D
M
G
T
I
L
L
G
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P05453
685
76532
T503
A
K
M
K
D
L
G
T
I
V
E
G
K
I
E
Red Bread Mold
Neurospora crassa
Q01372
460
49654
V288
P
S
N
V
T
T
E
V
K
S
V
E
M
H
H
Conservation
Percent
Protein Identity:
100
80.9
55
98.1
N.A.
98.5
32.5
N.A.
78.3
78.1
83.7
75.5
N.A.
57.5
N.A.
36
61.2
Protein Similarity:
100
80.9
56.1
98.8
N.A.
99
47.2
N.A.
81.1
78.9
87.3
80.5
N.A.
66.8
N.A.
53.3
74.2
P-Site Identity:
100
6.6
46.6
100
N.A.
100
26.6
N.A.
0
100
93.3
93.3
N.A.
86.6
N.A.
0
6.6
P-Site Similarity:
100
13.3
66.6
100
N.A.
100
46.6
N.A.
0
100
100
100
N.A.
100
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
40.2
35.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.1
52.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
0
0
0
0
7
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
60
7
0
0
60
14
14
7
0
0
0
7
0
0
0
% D
% Glu:
0
0
0
0
0
0
14
0
7
7
14
14
0
0
54
% E
% Phe:
0
0
7
0
0
0
0
7
0
7
0
0
0
0
0
% F
% Gly:
0
7
7
0
0
0
67
7
7
0
0
54
7
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
14
14
% H
% Ile:
0
0
7
7
0
0
0
0
7
20
0
0
0
7
0
% I
% Lys:
0
60
0
67
7
0
0
0
14
0
0
0
54
7
14
% K
% Leu:
7
7
0
7
7
7
0
0
0
0
54
7
0
40
0
% L
% Met:
0
0
7
0
0
47
7
0
0
0
7
0
14
7
0
% M
% Asn:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
7
0
0
0
14
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
0
7
0
0
0
0
0
0
0
7
0
0
% R
% Ser:
0
7
0
0
7
7
0
7
0
14
0
7
0
0
0
% S
% Thr:
7
0
0
0
14
14
0
54
14
7
7
0
14
0
0
% T
% Val:
7
7
0
14
0
0
0
20
54
47
14
7
7
14
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
54
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _