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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARSA All Species: 24.85
Human Site: S242 Identified Species: 68.33
UniProt: P15289 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P15289 NP_000478.2 507 53588 S242 G Q S F A E R S G R G P F G D
Chimpanzee Pan troglodytes XP_515228 680 72773 S415 G Q S F A E R S G R G P F G D
Rhesus Macaque Macaca mulatta XP_001113032 507 53693 S242 G Q N F A E R S G R G P F G D
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P50428 506 53758 S241 G Q S F T K R S G R G P F G D
Rat Rattus norvegicus Q32KJ9 526 57250 Q264 T P P L A N P Q S Q R L Y R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_424471 503 54522 S244 S Q E Y A G R S Q R G P F G D
Frog Xenopus laevis NP_001087428 507 56175 S242 S V Q Y T G Q S I R G R F G D
Zebra Danio Brachydanio rerio NP_001013561 499 54590 S241 G A D Y A G K S P R G P F G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P50473 567 62459 S284 S D D F S C T S R R G R Y G D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.5 96.6 N.A. N.A. 85.2 37.8 N.A. N.A. 62.7 55.6 56.2 N.A. N.A. N.A. N.A. 33.5
Protein Similarity: 100 74.1 97.8 N.A. N.A. 91.1 51.1 N.A. N.A. 72.9 70.2 70.8 N.A. N.A. N.A. N.A. 47.4
P-Site Identity: 100 100 93.3 N.A. N.A. 86.6 6.6 N.A. N.A. 66.6 40 60 N.A. N.A. N.A. N.A. 40
P-Site Similarity: 100 100 100 N.A. N.A. 93.3 20 N.A. N.A. 73.3 53.3 73.3 N.A. N.A. N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 67 0 0 0 0 0 0 0 0 0 12 % A
% Cys: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 23 0 0 0 0 0 0 0 0 0 0 0 89 % D
% Glu: 0 0 12 0 0 34 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 56 0 0 0 0 0 0 0 0 78 0 0 % F
% Gly: 56 0 0 0 0 34 0 0 45 0 89 0 0 89 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 12 12 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 12 0 0 0 0 0 0 0 12 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 12 0 0 12 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 12 12 0 0 0 12 0 12 0 0 67 0 0 0 % P
% Gln: 0 56 12 0 0 0 12 12 12 12 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 56 0 12 89 12 23 0 12 0 % R
% Ser: 34 0 34 0 12 0 0 89 12 0 0 0 0 0 0 % S
% Thr: 12 0 0 0 23 0 12 0 0 0 0 0 0 0 0 % T
% Val: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 34 0 0 0 0 0 0 0 0 23 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _