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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARSA
All Species:
25.76
Human Site:
Y223
Identified Species:
70.83
UniProt:
P15289
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15289
NP_000478.2
507
53588
Y223
D
R
P
F
F
L
Y
Y
A
S
H
H
T
H
Y
Chimpanzee
Pan troglodytes
XP_515228
680
72773
Y396
D
R
P
F
F
L
Y
Y
A
S
H
H
T
H
Y
Rhesus Macaque
Macaca mulatta
XP_001113032
507
53693
Y223
D
R
P
F
F
L
Y
Y
A
S
H
H
T
H
Y
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P50428
506
53758
Y222
G
R
P
F
F
L
Y
Y
A
S
H
H
T
H
Y
Rat
Rattus norvegicus
Q32KJ9
526
57250
V245
G
R
P
F
L
L
Y
V
G
L
A
H
M
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424471
503
54522
Y225
G
V
P
F
L
L
Y
Y
A
S
H
H
T
H
Y
Frog
Xenopus laevis
NP_001087428
507
56175
Y223
N
K
P
F
F
L
Y
Y
A
S
H
H
T
H
Y
Zebra Danio
Brachydanio rerio
NP_001013561
499
54590
Y222
N
R
P
F
F
L
Y
Y
P
S
H
H
T
H
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P50473
567
62459
V265
N
K
P
F
F
M
Y
V
S
F
A
H
M
H
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.5
96.6
N.A.
N.A.
85.2
37.8
N.A.
N.A.
62.7
55.6
56.2
N.A.
N.A.
N.A.
N.A.
33.5
Protein Similarity:
100
74.1
97.8
N.A.
N.A.
91.1
51.1
N.A.
N.A.
72.9
70.2
70.8
N.A.
N.A.
N.A.
N.A.
47.4
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
46.6
N.A.
N.A.
80
86.6
86.6
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
46.6
N.A.
N.A.
80
100
93.3
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
67
0
23
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
34
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
100
78
0
0
0
0
12
0
0
0
0
0
% F
% Gly:
34
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
78
100
0
100
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
23
89
0
0
0
12
0
0
0
0
0
% L
% Met:
0
0
0
0
0
12
0
0
0
0
0
0
23
0
0
% M
% Asn:
34
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
100
0
0
0
0
0
12
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
12
78
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
78
0
12
% T
% Val:
0
12
0
0
0
0
0
23
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
100
78
0
0
0
0
0
0
78
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _