KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARSA
All Species:
23.33
Human Site:
Y376
Identified Species:
64.17
UniProt:
P15289
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15289
NP_000478.2
507
53588
Y376
P
R
Q
S
L
F
F
Y
P
S
Y
P
D
E
V
Chimpanzee
Pan troglodytes
XP_515228
680
72773
Y549
P
R
R
S
L
F
F
Y
P
S
Y
P
D
E
V
Rhesus Macaque
Macaca mulatta
XP_001113032
507
53693
Y376
P
R
Q
S
L
F
F
Y
P
S
D
P
D
E
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P50428
506
53758
Y375
P
R
K
S
V
F
F
Y
P
P
Y
P
D
E
I
Rat
Rattus norvegicus
Q32KJ9
526
57250
P409
G
H
R
V
L
F
H
P
N
S
G
A
A
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424471
503
54522
Y378
P
R
Q
T
M
F
F
Y
P
P
S
P
D
P
L
Frog
Xenopus laevis
NP_001087428
507
56175
Y376
P
R
N
T
F
H
Y
Y
P
S
S
I
D
R
N
Zebra Danio
Brachydanio rerio
NP_001013561
499
54590
Y375
K
R
Q
T
M
F
Y
Y
P
T
D
P
S
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P50473
567
62459
Y418
S
P
H
D
D
F
F
Y
Y
C
K
D
T
L
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.5
96.6
N.A.
N.A.
85.2
37.8
N.A.
N.A.
62.7
55.6
56.2
N.A.
N.A.
N.A.
N.A.
33.5
Protein Similarity:
100
74.1
97.8
N.A.
N.A.
91.1
51.1
N.A.
N.A.
72.9
70.2
70.8
N.A.
N.A.
N.A.
N.A.
47.4
P-Site Identity:
100
93.3
93.3
N.A.
N.A.
73.3
20
N.A.
N.A.
60
40
40
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
93.3
N.A.
N.A.
93.3
26.6
N.A.
N.A.
80
53.3
66.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
12
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
0
0
0
12
12
0
0
0
0
0
23
12
67
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
45
12
% E
% Phe:
0
0
0
0
12
89
67
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
0
0
0
0
0
0
12
0
0
12
0
% G
% His:
0
12
12
0
0
12
12
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% I
% Lys:
12
0
12
0
0
0
0
0
0
0
12
0
0
0
12
% K
% Leu:
0
0
0
0
45
0
0
0
0
0
0
0
0
12
12
% L
% Met:
0
0
0
0
23
0
0
0
0
0
0
0
0
0
12
% M
% Asn:
0
0
12
0
0
0
0
0
12
0
0
0
0
0
12
% N
% Pro:
67
12
0
0
0
0
0
12
78
23
0
67
0
12
0
% P
% Gln:
0
0
45
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
78
23
0
0
0
0
0
0
0
0
0
0
12
0
% R
% Ser:
12
0
0
45
0
0
0
0
0
56
23
0
12
0
0
% S
% Thr:
0
0
0
34
0
0
0
0
0
12
0
0
12
0
0
% T
% Val:
0
0
0
12
12
0
0
0
0
0
0
0
0
12
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
23
89
12
0
34
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _