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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACPP All Species: 25.45
Human Site: Y330 Identified Species: 62.22
UniProt: P15309 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P15309 NP_001090.2 386 44566 Y330 G E Y F V E M Y Y R N E T Q H
Chimpanzee Pan troglodytes XP_001149173 386 44568 Y330 G E Y F V E M Y Y R N E T Q H
Rhesus Macaque Macaca mulatta XP_001115549 418 48167 Y330 G E Y F V E M Y Y R N E T Q H
Dog Lupus familis XP_542782 624 69720 Y536 G E Y F V E M Y Y R N E T Q H
Cat Felis silvestris
Mouse Mus musculus Q8CE08 381 43699 Y329 G G H F V E M Y Y R N E T Q N
Rat Rattus norvegicus P20646 381 43832 Y329 G G T F V E M Y Y R N E T Q N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514148 518 59648 Y442 G K Y N I E M Y Y R N N S W N
Chicken Gallus gallus
Frog Xenopus laevis B1H1P9 432 48224 M330 S G N F T V Q M Y F R N E S G
Zebra Danio Brachydanio rerio NP_001013355 414 47189 P335 S P Y A V S L P G C S Q R C P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10944 422 48390 C363 P E D W E A E C G L K T S F Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 85.6 51.9 N.A. 80.5 78.2 N.A. 51.5 N.A. 45.8 45.6 N.A. N.A. N.A. 30.8 N.A.
Protein Similarity: 100 99.2 88.5 57.2 N.A. 88 85.4 N.A. 63.5 N.A. 62 63 N.A. N.A. N.A. 51.1 N.A.
P-Site Identity: 100 100 100 100 N.A. 80 80 N.A. 53.3 N.A. 13.3 13.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 86.6 N.A. 80 N.A. 13.3 33.3 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 10 0 0 0 10 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 50 0 0 10 70 10 0 0 0 0 60 10 0 0 % E
% Phe: 0 0 0 70 0 0 0 0 0 10 0 0 0 10 0 % F
% Gly: 70 30 0 0 0 0 0 0 20 0 0 0 0 0 10 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 40 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 70 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 10 0 0 0 0 0 0 70 20 0 0 30 % N
% Pro: 10 10 0 0 0 0 0 10 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 10 0 60 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 70 10 0 10 0 0 % R
% Ser: 20 0 0 0 0 10 0 0 0 0 10 0 20 10 0 % S
% Thr: 0 0 10 0 10 0 0 0 0 0 0 10 60 0 0 % T
% Val: 0 0 0 0 70 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 60 0 0 0 0 70 80 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _