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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V1B1
All Species:
59.09
Human Site:
S393
Identified Species:
92.86
UniProt:
P15313
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15313
NP_001683.2
513
56833
S393
I
N
V
L
P
S
L
S
R
L
M
K
S
A
I
Chimpanzee
Pan troglodytes
XP_001145161
513
56950
S393
I
N
V
L
P
S
L
S
R
L
M
K
S
A
I
Rhesus Macaque
Macaca mulatta
XP_001100824
513
56815
S393
I
N
V
L
P
S
L
S
R
L
M
K
S
A
I
Dog
Lupus familis
XP_531858
522
57874
S393
V
N
V
L
P
S
L
S
R
L
M
K
S
A
I
Cat
Felis silvestris
Mouse
Mus musculus
NP_598918
513
56772
S393
I
N
V
L
P
S
L
S
R
L
M
K
S
A
I
Rat
Rattus norvegicus
P62815
511
56532
S399
I
N
V
L
P
S
L
S
R
L
M
K
S
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P49712
453
50207
R353
A
I
G
E
G
M
T
R
K
D
H
A
D
V
S
Frog
Xenopus laevis
NP_001090361
506
56195
S384
I
N
V
L
P
S
L
S
R
L
M
K
S
A
I
Zebra Danio
Brachydanio rerio
XP_002663572
509
56459
S398
I
N
V
L
P
S
L
S
R
L
M
K
S
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P31409
490
54531
S379
V
N
V
L
P
S
L
S
R
L
M
K
S
A
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19626
491
54732
S379
I
N
V
L
P
S
L
S
R
L
M
K
S
A
I
Sea Urchin
Strong. purpuratus
XP_794151
487
54097
S376
I
N
V
L
P
S
L
S
R
L
M
K
S
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZN1
487
54286
S376
I
N
V
L
P
S
L
S
R
L
M
K
S
A
I
Baker's Yeast
Sacchar. cerevisiae
P16140
517
57731
S380
I
N
V
L
P
S
L
S
R
L
M
K
S
A
I
Red Bread Mold
Neurospora crassa
P11593
513
56790
S374
I
N
V
L
P
S
L
S
R
L
M
K
S
A
I
Conservation
Percent
Protein Identity:
100
99.2
99.6
93.4
N.A.
93.7
84.5
N.A.
N.A.
76.2
86.9
84
N.A.
81.8
N.A.
79.1
82.2
Protein Similarity:
100
99.4
99.6
96.5
N.A.
97
91.2
N.A.
N.A.
81.4
92.7
91
N.A.
88.3
N.A.
87.1
87.3
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
0
100
100
N.A.
93.3
N.A.
100
100
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
100
100
N.A.
100
N.A.
100
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
73.2
73.8
74
Protein Similarity:
N.A.
N.A.
N.A.
82.6
83.7
83.8
P-Site Identity:
N.A.
N.A.
N.A.
100
100
100
P-Site Similarity:
N.A.
N.A.
N.A.
100
100
100
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
0
0
0
0
7
0
94
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% D
% Glu:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
80
7
0
0
0
0
0
0
0
0
0
0
0
0
94
% I
% Lys:
0
0
0
0
0
0
0
0
7
0
0
94
0
0
0
% K
% Leu:
0
0
0
94
0
0
94
0
0
94
0
0
0
0
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
94
0
0
0
0
% M
% Asn:
0
94
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
94
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
7
94
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
94
0
94
0
0
0
0
94
0
7
% S
% Thr:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% T
% Val:
14
0
94
0
0
0
0
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _