KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V1B1
All Species:
39.7
Human Site:
Y159
Identified Species:
62.38
UniProt:
P15313
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15313
NP_001683.2
513
56833
Y159
I
N
P
H
S
R
I
Y
P
E
E
M
I
Q
T
Chimpanzee
Pan troglodytes
XP_001145161
513
56950
Y159
I
N
P
H
S
R
I
Y
P
E
E
M
I
Q
T
Rhesus Macaque
Macaca mulatta
XP_001100824
513
56815
Y159
I
N
P
H
S
R
I
Y
P
E
E
M
I
Q
T
Dog
Lupus familis
XP_531858
522
57874
Y159
I
N
P
H
D
R
I
Y
P
E
E
M
I
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
NP_598918
513
56772
Y159
I
N
P
H
D
R
I
Y
P
E
E
M
I
Q
T
Rat
Rattus norvegicus
P62815
511
56532
Y165
I
N
P
Q
C
R
I
Y
P
E
E
M
I
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P49712
453
50207
I130
S
I
A
R
G
Q
K
I
P
I
F
S
A
A
G
Frog
Xenopus laevis
NP_001090361
506
56195
Y150
I
N
P
Y
G
R
T
Y
P
E
E
M
I
Q
T
Zebra Danio
Brachydanio rerio
XP_002663572
509
56459
Y164
I
N
P
Q
C
R
I
Y
P
E
E
M
I
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P31409
490
54531
I153
E
E
M
I
Q
T
G
I
S
A
I
D
V
M
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19626
491
54732
Y147
I
N
P
W
S
R
I
Y
P
E
E
M
I
Q
T
Sea Urchin
Strong. purpuratus
XP_794151
487
54097
I150
E
E
M
I
Q
T
G
I
S
A
I
D
V
M
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZN1
487
54286
S148
E
M
I
Q
T
G
I
S
T
I
D
V
M
N
S
Baker's Yeast
Sacchar. cerevisiae
P16140
517
57731
Y146
I
N
P
Y
A
R
I
Y
P
E
E
M
I
S
T
Red Bread Mold
Neurospora crassa
P11593
513
56790
A147
M
I
S
T
G
I
S
A
I
D
T
M
N
S
I
Conservation
Percent
Protein Identity:
100
99.2
99.6
93.4
N.A.
93.7
84.5
N.A.
N.A.
76.2
86.9
84
N.A.
81.8
N.A.
79.1
82.2
Protein Similarity:
100
99.4
99.6
96.5
N.A.
97
91.2
N.A.
N.A.
81.4
92.7
91
N.A.
88.3
N.A.
87.1
87.3
P-Site Identity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
N.A.
6.6
80
86.6
N.A.
0
N.A.
93.3
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
N.A.
13.3
86.6
86.6
N.A.
6.6
N.A.
93.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
73.2
73.8
74
Protein Similarity:
N.A.
N.A.
N.A.
82.6
83.7
83.8
P-Site Identity:
N.A.
N.A.
N.A.
6.6
80
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
40
93.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
0
0
7
0
14
0
0
7
7
0
% A
% Cys:
0
0
0
0
14
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
14
0
0
0
0
7
7
14
0
0
0
% D
% Glu:
20
14
0
0
0
0
0
0
0
67
67
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
0
0
0
20
7
14
0
0
0
0
0
0
0
7
% G
% His:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
67
14
7
14
0
7
67
20
7
14
14
0
67
0
7
% I
% Lys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
7
7
14
0
0
0
0
0
0
0
0
74
7
14
0
% M
% Asn:
0
67
0
0
0
0
0
0
0
0
0
0
7
7
14
% N
% Pro:
0
0
67
0
0
0
0
0
74
0
0
0
0
0
0
% P
% Gln:
0
0
0
20
14
7
0
0
0
0
0
0
0
60
0
% Q
% Arg:
0
0
0
7
0
67
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
0
7
0
27
0
7
7
14
0
0
7
0
14
7
% S
% Thr:
0
0
0
7
7
14
7
0
7
0
7
0
0
0
67
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
7
14
0
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
14
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _