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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V1B1
All Species:
30
Human Site:
Y216
Identified Species:
47.14
UniProt:
P15313
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15313
NP_001683.2
513
56833
Y216
K
S
K
A
V
L
D
Y
H
D
D
N
F
A
I
Chimpanzee
Pan troglodytes
XP_001145161
513
56950
Y216
K
S
K
A
V
L
D
Y
H
D
D
N
F
A
I
Rhesus Macaque
Macaca mulatta
XP_001100824
513
56815
Y216
K
S
K
A
V
L
D
Y
H
D
D
N
F
A
I
Dog
Lupus familis
XP_531858
522
57874
Y216
K
S
K
A
V
L
D
Y
H
D
D
N
F
A
I
Cat
Felis silvestris
Mouse
Mus musculus
NP_598918
513
56772
Y216
K
S
K
A
V
L
D
Y
H
E
D
N
F
A
I
Rat
Rattus norvegicus
P62815
511
56532
Y222
K
S
K
D
V
V
D
Y
S
E
E
N
F
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P49712
453
50207
M179
F
A
A
M
G
V
N
M
E
T
A
R
F
F
K
Frog
Xenopus laevis
NP_001090361
506
56195
Y207
K
S
K
D
V
M
D
Y
S
E
E
N
F
A
I
Zebra Danio
Brachydanio rerio
XP_002663572
509
56459
Y221
K
S
K
D
V
M
D
Y
S
E
D
N
F
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P31409
490
54531
D202
P
G
K
S
V
L
D
D
H
T
D
N
F
A
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19626
491
54732
Q204
L
P
D
R
P
H
E
Q
T
N
F
A
I
V
F
Sea Urchin
Strong. purpuratus
XP_794151
487
54097
G199
P
D
K
G
V
L
D
G
H
E
D
N
F
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZN1
487
54286
H198
K
S
D
N
L
L
E
H
Q
E
D
D
N
F
A
Baker's Yeast
Sacchar. cerevisiae
P16140
517
57731
G203
P
T
K
D
V
H
D
G
H
E
E
N
F
S
I
Red Bread Mold
Neurospora crassa
P11593
513
56790
G197
T
N
K
G
V
H
D
G
H
E
E
N
F
S
I
Conservation
Percent
Protein Identity:
100
99.2
99.6
93.4
N.A.
93.7
84.5
N.A.
N.A.
76.2
86.9
84
N.A.
81.8
N.A.
79.1
82.2
Protein Similarity:
100
99.4
99.6
96.5
N.A.
97
91.2
N.A.
N.A.
81.4
92.7
91
N.A.
88.3
N.A.
87.1
87.3
P-Site Identity:
100
100
100
100
N.A.
93.3
66.6
N.A.
N.A.
6.6
66.6
73.3
N.A.
66.6
N.A.
0
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
86.6
N.A.
N.A.
26.6
86.6
86.6
N.A.
73.3
N.A.
13.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
73.2
73.8
74
Protein Similarity:
N.A.
N.A.
N.A.
82.6
83.7
83.8
P-Site Identity:
N.A.
N.A.
N.A.
26.6
46.6
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
60
73.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
34
0
0
0
0
0
0
7
7
0
67
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
14
27
0
0
80
7
0
27
60
7
0
0
0
% D
% Glu:
0
0
0
0
0
0
14
0
7
54
27
0
0
0
0
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
7
0
87
14
7
% F
% Gly:
0
7
0
14
7
0
0
20
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
20
0
7
60
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
80
% I
% Lys:
60
0
80
0
0
0
0
0
0
0
0
0
0
0
7
% K
% Leu:
7
0
0
0
7
54
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
7
0
14
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
7
0
0
7
0
0
7
0
80
7
0
0
% N
% Pro:
20
7
0
0
7
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% Q
% Arg:
0
0
0
7
0
0
0
0
0
0
0
7
0
0
0
% R
% Ser:
0
60
0
7
0
0
0
0
20
0
0
0
0
14
0
% S
% Thr:
7
7
0
0
0
0
0
0
7
14
0
0
0
0
0
% T
% Val:
0
0
0
0
80
14
0
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _