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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNE1
All Species:
31.21
Human Site:
S74
Identified Species:
85.83
UniProt:
P15382
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15382
NP_000210.2
129
14675
S74
R
S
K
K
L
E
H
S
N
D
P
F
N
V
Y
Chimpanzee
Pan troglodytes
XP_531545
129
14684
S74
R
S
K
K
L
E
H
S
N
D
P
F
N
V
Y
Rhesus Macaque
Macaca mulatta
XP_001088840
129
14690
S74
R
S
K
K
L
E
H
S
N
D
P
F
N
V
Y
Dog
Lupus familis
XP_544868
394
43702
S339
R
S
K
K
L
E
H
S
H
D
P
F
N
V
Y
Cat
Felis silvestris
Mouse
Mus musculus
P23299
129
14559
S74
R
S
K
K
L
E
H
S
H
D
P
F
N
V
Y
Rat
Rattus norvegicus
P15383
130
14680
S75
R
S
K
K
L
E
H
S
H
D
P
F
N
V
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513415
148
16925
S83
R
S
K
K
L
E
H
S
H
D
P
Y
N
I
Y
Chicken
Gallus gallus
XP_425550
126
14193
S72
R
A
R
R
L
E
D
S
H
N
P
Y
N
T
Y
Frog
Xenopus laevis
NP_001082348
118
13292
K64
F
S
Y
I
R
S
K
K
R
E
H
S
G
D
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
94.5
27.1
N.A.
75.9
76.1
N.A.
53.3
48
44.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.4
97.6
30.2
N.A.
84.5
82.3
N.A.
68.2
73.6
60.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
80
46.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
86.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
0
0
78
0
0
0
12
0
% D
% Glu:
0
0
0
0
0
89
0
0
0
12
0
0
0
0
0
% E
% Phe:
12
0
0
0
0
0
0
0
0
0
0
67
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% G
% His:
0
0
0
0
0
0
78
0
56
0
12
0
0
0
0
% H
% Ile:
0
0
0
12
0
0
0
0
0
0
0
0
0
12
0
% I
% Lys:
0
0
78
78
0
0
12
12
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
89
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
34
12
0
0
89
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
89
0
0
0
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
89
0
12
12
12
0
0
0
12
0
0
0
0
0
0
% R
% Ser:
0
89
0
0
0
12
0
89
0
0
0
12
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
67
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
0
0
0
0
0
0
23
0
0
89
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _