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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CD19 All Species: 16.67
Human Site: Y421 Identified Species: 61.11
UniProt: P15391 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P15391 NP_001761.3 556 61128 Y421 S E E D S E F Y E N D S N L G
Chimpanzee Pan troglodytes XP_510906 405 44510 L276 F Y E N D S N L G Q D Q L S Q
Rhesus Macaque Macaca mulatta XP_001103043 557 61015 Y422 S E E G S E F Y E N D S N F G
Dog Lupus familis XP_860299 559 61228 Y424 S E E G S E F Y E N D S N R G
Cat Felis silvestris
Mouse Mus musculus P25918 547 60145 Y414 S E E G S E F Y E N D S N L G
Rat Rattus norvegicus NP_001013255 547 60241 Y414 S E E G S E F Y E N D S N L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515814 275 29487 S147 A L A Y V T I S L A V V V I F
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72.6 91.7 72.2 N.A. 66.3 65.2 N.A. 27.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 72.6 94.2 79.4 N.A. 75.1 74.2 N.A. 35.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 86.6 86.6 N.A. 93.3 86.6 N.A. 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 86.6 86.6 N.A. 93.3 86.6 N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 15 0 0 0 0 0 0 15 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 15 15 0 0 0 0 0 86 0 0 0 0 % D
% Glu: 0 72 86 0 0 72 0 0 72 0 0 0 0 0 15 % E
% Phe: 15 0 0 0 0 0 72 0 0 0 0 0 0 15 15 % F
% Gly: 0 0 0 58 0 0 0 0 15 0 0 0 0 0 58 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 15 0 0 0 0 0 0 15 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 15 0 0 0 0 0 15 15 0 0 0 15 43 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 15 0 0 15 0 0 72 0 0 72 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 15 0 15 0 0 15 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % R
% Ser: 72 0 0 0 72 15 0 15 0 0 0 72 0 15 0 % S
% Thr: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 15 0 0 0 0 0 15 15 15 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 15 0 15 0 0 0 72 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _