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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPGD
All Species:
0.91
Human Site:
T258
Identified Species:
2.22
UniProt:
P15428
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15428
NP_000851.2
266
28977
T258
I
H
F
Q
D
Y
D
T
T
P
F
Q
A
K
T
Chimpanzee
Pan troglodytes
XP_001157095
143
15515
M136
E
G
G
I
I
I
N
M
S
S
L
A
A
H
H
Rhesus Macaque
Macaca mulatta
XP_001087715
266
28915
A258
I
H
F
Q
D
Y
D
A
T
P
F
Q
A
K
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCC1
269
29162
I258
I
H
F
Q
D
Y
D
I
S
P
L
L
V
K
A
Rat
Rattus norvegicus
O08699
266
28921
L258
I
H
F
Q
D
Y
D
L
F
P
S
F
S
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086976
264
28708
S248
A
V
M
K
I
T
T
S
R
G
I
H
F
E
E
Zebra Danio
Brachydanio rerio
XP_694331
221
24242
K211
V
K
Y
K
D
D
F
K
Q
R
M
D
K
Y
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54398
256
28980
M223
Q
M
P
E
E
A
A
M
Q
M
I
H
A
M
E
Honey Bee
Apis mellifera
XP_623818
263
28758
L256
Y
A
V
E
F
P
P
L
K
K
I
E
L
Q
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796537
298
32477
G286
M
R
C
T
P
Q
N
G
I
D
Y
K
K
F
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.7
98.8
N.A.
N.A.
88.4
88.7
N.A.
N.A.
N.A.
68.8
46.9
N.A.
26.3
34.9
N.A.
36.9
Protein Similarity:
100
53.7
99.6
N.A.
N.A.
92.9
92.8
N.A.
N.A.
N.A.
81.9
62
N.A.
46.6
55.2
N.A.
56.3
P-Site Identity:
100
6.6
86.6
N.A.
N.A.
60
60
N.A.
N.A.
N.A.
0
6.6
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
20
93.3
N.A.
N.A.
66.6
66.6
N.A.
N.A.
N.A.
20
26.6
N.A.
20
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
10
10
10
0
0
0
10
40
0
20
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
50
10
40
0
0
10
0
10
0
0
0
% D
% Glu:
10
0
0
20
10
0
0
0
0
0
0
10
0
10
20
% E
% Phe:
0
0
40
0
10
0
10
0
10
0
20
10
10
10
0
% F
% Gly:
0
10
10
0
0
0
0
10
0
10
0
0
0
0
10
% G
% His:
0
40
0
0
0
0
0
0
0
0
0
20
0
10
10
% H
% Ile:
40
0
0
10
20
10
0
10
10
0
30
0
0
0
0
% I
% Lys:
0
10
0
20
0
0
0
10
10
10
0
10
20
40
0
% K
% Leu:
0
0
0
0
0
0
0
20
0
0
20
10
10
0
10
% L
% Met:
10
10
10
0
0
0
0
20
0
10
10
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
10
10
10
0
0
40
0
0
0
0
0
% P
% Gln:
10
0
0
40
0
10
0
0
20
0
0
20
0
10
0
% Q
% Arg:
0
10
0
0
0
0
0
0
10
10
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
10
20
10
10
0
10
0
10
% S
% Thr:
0
0
0
10
0
10
10
10
20
0
0
0
0
0
10
% T
% Val:
10
10
10
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
10
0
0
40
0
0
0
0
10
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _