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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPGD
All Species:
13.64
Human Site:
T74
Identified Species:
33.33
UniProt:
P15428
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15428
NP_000851.2
266
28977
T74
D
Q
Q
Q
L
R
D
T
F
R
K
V
V
D
H
Chimpanzee
Pan troglodytes
XP_001157095
143
15515
Rhesus Macaque
Macaca mulatta
XP_001087715
266
28915
T74
D
Q
Q
Q
L
R
D
T
F
R
K
V
V
D
H
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCC1
269
29162
T74
D
Q
K
Q
L
R
D
T
F
R
K
V
V
D
H
Rat
Rattus norvegicus
O08699
266
28921
T74
D
Q
K
Q
L
R
D
T
F
R
K
V
V
D
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086976
264
28708
A74
D
Q
K
Q
L
K
D
A
F
R
K
T
V
E
H
Zebra Danio
Brachydanio rerio
XP_694331
221
24242
V41
L
V
D
L
N
Q
S
V
G
E
E
C
K
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54398
256
28980
M45
H
R
M
E
N
V
E
M
M
K
K
L
Q
A
I
Honey Bee
Apis mellifera
XP_623818
263
28758
V77
N
I
N
E
F
E
A
V
F
K
K
V
V
N
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796537
298
32477
A114
S
K
D
Q
L
E
D
A
F
S
K
T
L
E
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.7
98.8
N.A.
N.A.
88.4
88.7
N.A.
N.A.
N.A.
68.8
46.9
N.A.
26.3
34.9
N.A.
36.9
Protein Similarity:
100
53.7
99.6
N.A.
N.A.
92.9
92.8
N.A.
N.A.
N.A.
81.9
62
N.A.
46.6
55.2
N.A.
56.3
P-Site Identity:
100
0
100
N.A.
N.A.
93.3
93.3
N.A.
N.A.
N.A.
66.6
0
N.A.
6.6
26.6
N.A.
40
P-Site Similarity:
100
0
100
N.A.
N.A.
100
100
N.A.
N.A.
N.A.
86.6
13.3
N.A.
40
53.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
20
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
50
0
20
0
0
0
60
0
0
0
0
0
0
40
20
% D
% Glu:
0
0
0
20
0
20
10
0
0
10
10
0
0
20
0
% E
% Phe:
0
0
0
0
10
0
0
0
70
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
10
30
0
0
10
0
0
0
20
80
0
10
0
0
% K
% Leu:
10
0
0
10
60
0
0
0
0
0
0
10
10
0
0
% L
% Met:
0
0
10
0
0
0
0
10
10
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
20
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
50
20
60
0
10
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
10
0
0
0
40
0
0
0
50
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
10
0
0
10
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
40
0
0
0
20
0
0
0
% T
% Val:
0
10
0
0
0
10
0
20
0
0
0
50
60
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _