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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPGD
All Species:
16.06
Human Site:
Y203
Identified Species:
39.26
UniProt:
P15428
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15428
NP_000851.2
266
28977
Y203
K
E
E
N
M
G
Q
Y
I
E
Y
K
D
H
I
Chimpanzee
Pan troglodytes
XP_001157095
143
15515
H81
T
F
R
K
V
V
D
H
F
G
R
L
D
I
L
Rhesus Macaque
Macaca mulatta
XP_001087715
266
28915
Y203
K
E
E
N
M
G
Q
Y
I
E
Y
K
D
H
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCC1
269
29162
Y203
K
E
E
N
M
G
Q
Y
I
E
Y
K
D
Q
I
Rat
Rattus norvegicus
O08699
266
28921
Y203
K
E
E
N
M
G
Q
Y
I
E
Y
T
D
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086976
264
28708
S193
V
D
T
P
L
L
E
S
I
E
K
E
E
N
M
Zebra Danio
Brachydanio rerio
XP_694331
221
24242
Y156
P
V
Y
T
A
T
K
Y
G
V
I
G
F
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54398
256
28980
K168
F
T
R
S
M
G
D
K
M
I
Y
Q
K
T
G
Honey Bee
Apis mellifera
XP_623818
263
28758
D201
N
P
L
S
K
S
F
D
F
V
T
Q
N
D
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796537
298
32477
I231
P
S
F
S
E
T
A
I
L
Q
Q
M
K
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.7
98.8
N.A.
N.A.
88.4
88.7
N.A.
N.A.
N.A.
68.8
46.9
N.A.
26.3
34.9
N.A.
36.9
Protein Similarity:
100
53.7
99.6
N.A.
N.A.
92.9
92.8
N.A.
N.A.
N.A.
81.9
62
N.A.
46.6
55.2
N.A.
56.3
P-Site Identity:
100
6.6
100
N.A.
N.A.
93.3
86.6
N.A.
N.A.
N.A.
13.3
6.6
N.A.
20
0
N.A.
0
P-Site Similarity:
100
26.6
100
N.A.
N.A.
93.3
86.6
N.A.
N.A.
N.A.
60
13.3
N.A.
40
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
20
10
0
0
0
0
50
10
0
% D
% Glu:
0
40
40
0
10
0
10
0
0
50
0
10
10
0
0
% E
% Phe:
10
10
10
0
0
0
10
0
20
0
0
0
10
0
10
% F
% Gly:
0
0
0
0
0
50
0
0
10
10
0
10
0
10
10
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
20
0
% H
% Ile:
0
0
0
0
0
0
0
10
50
10
10
0
0
10
40
% I
% Lys:
40
0
0
10
10
0
10
10
0
0
10
30
20
0
0
% K
% Leu:
0
0
10
0
10
10
0
0
10
0
0
10
0
0
20
% L
% Met:
0
0
0
0
50
0
0
0
10
0
0
10
0
0
10
% M
% Asn:
10
0
0
40
0
0
0
0
0
0
0
0
10
10
0
% N
% Pro:
20
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
40
0
0
10
10
20
0
20
0
% Q
% Arg:
0
0
20
0
0
0
0
0
0
0
10
0
0
0
10
% R
% Ser:
0
10
0
30
0
10
0
10
0
0
0
0
0
10
0
% S
% Thr:
10
10
10
10
0
20
0
0
0
0
10
10
0
10
0
% T
% Val:
10
10
0
0
10
10
0
0
0
20
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
50
0
0
50
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _