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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPGD
All Species:
6.36
Human Site:
Y216
Identified Species:
15.56
UniProt:
P15428
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15428
NP_000851.2
266
28977
Y216
H
I
K
D
M
I
K
Y
Y
G
I
L
D
P
P
Chimpanzee
Pan troglodytes
XP_001157095
143
15515
V94
I
L
V
N
N
A
G
V
N
N
E
K
N
W
E
Rhesus Macaque
Macaca mulatta
XP_001087715
266
28915
Y216
H
I
K
D
M
I
K
Y
Y
G
I
L
D
P
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCC1
269
29162
F216
Q
I
K
A
M
M
K
F
Y
G
V
L
H
P
S
Rat
Rattus norvegicus
O08699
266
28921
F216
Q
I
K
A
M
M
K
F
Y
G
I
L
D
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086976
264
28708
Y206
N
M
G
D
F
F
K
Y
K
D
R
I
K
D
M
Zebra Danio
Brachydanio rerio
XP_694331
221
24242
S169
S
R
A
M
A
D
A
S
E
Q
G
N
Y
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54398
256
28980
M181
T
G
V
M
F
M
A
M
C
P
G
L
T
N
S
Honey Bee
Apis mellifera
XP_623818
263
28758
K214
D
F
Y
N
C
L
G
K
D
I
P
Q
T
P
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796537
298
32477
V244
G
L
I
N
H
N
P
V
A
E
A
I
Y
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.7
98.8
N.A.
N.A.
88.4
88.7
N.A.
N.A.
N.A.
68.8
46.9
N.A.
26.3
34.9
N.A.
36.9
Protein Similarity:
100
53.7
99.6
N.A.
N.A.
92.9
92.8
N.A.
N.A.
N.A.
81.9
62
N.A.
46.6
55.2
N.A.
56.3
P-Site Identity:
100
0
100
N.A.
N.A.
53.3
66.6
N.A.
N.A.
N.A.
20
0
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
20
100
N.A.
N.A.
73.3
80
N.A.
N.A.
N.A.
40
0
N.A.
13.3
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
20
10
10
20
0
10
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
10
0
0
30
0
10
0
0
10
10
0
0
30
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
10
10
0
0
0
20
% E
% Phe:
0
10
0
0
20
10
0
20
0
0
0
0
0
0
0
% F
% Gly:
10
10
10
0
0
0
20
0
0
40
20
0
0
20
0
% G
% His:
20
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
10
40
10
0
0
20
0
0
0
10
30
20
0
0
0
% I
% Lys:
0
0
40
0
0
0
50
10
10
0
0
10
10
0
0
% K
% Leu:
0
20
0
0
0
10
0
0
0
0
0
50
0
0
0
% L
% Met:
0
10
0
20
40
30
0
10
0
0
0
0
0
0
10
% M
% Asn:
10
0
0
30
10
10
0
0
10
10
0
10
10
10
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
10
10
0
0
50
20
% P
% Gln:
20
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
30
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% T
% Val:
0
0
20
0
0
0
0
20
0
0
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
10
0
0
0
0
30
40
0
0
0
20
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _