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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VAV1
All Species:
33.64
Human Site:
Y541
Identified Species:
67.27
UniProt:
P15498
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15498
NP_005419.2
845
98314
Y541
M
L
L
R
G
T
F
Y
Q
G
Y
R
C
H
R
Chimpanzee
Pan troglodytes
XP_512321
790
91847
Y486
M
L
L
R
G
T
F
Y
Q
G
Y
R
C
H
R
Rhesus Macaque
Macaca mulatta
XP_001083337
847
97793
Y539
M
L
L
R
G
T
F
Y
Q
G
Y
L
C
F
K
Dog
Lupus familis
XP_542134
845
98413
Y541
M
L
L
R
G
T
F
Y
Q
G
Y
R
C
H
R
Cat
Felis silvestris
Mouse
Mus musculus
P27870
845
98118
Y541
M
L
L
R
G
T
F
Y
Q
G
Y
R
C
Y
R
Rat
Rattus norvegicus
P54100
843
97935
Y541
M
L
L
R
G
T
F
Y
Q
G
Y
R
C
Y
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505586
846
97900
Y539
M
F
L
R
G
T
F
Y
Q
G
Y
L
C
T
K
Chicken
Gallus gallus
NP_996745
846
97797
Y539
M
L
L
R
G
T
F
Y
Q
G
Y
L
C
S
K
Frog
Xenopus laevis
NP_001086991
845
97765
F543
M
L
L
R
G
L
F
F
Q
G
Y
R
C
C
R
Zebra Danio
Brachydanio rerio
NP_001119865
822
94769
N532
M
L
L
R
G
I
F
N
Q
G
Y
L
C
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NHV9
793
91337
Y522
G
K
T
A
F
T
L
Y
L
K
S
E
H
E
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q45FX5
1007
113536
Y640
K
L
M
K
G
L
Q
Y
Q
G
Y
K
C
E
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.1
58.9
96.2
N.A.
93.1
92.9
N.A.
50.9
59
71.9
55.6
N.A.
32.6
N.A.
28.7
N.A.
Protein Similarity:
100
93.4
75.8
97.8
N.A.
96.2
96.2
N.A.
69.5
75.1
84.1
72.7
N.A.
52.7
N.A.
46.5
N.A.
P-Site Identity:
100
100
80
100
N.A.
93.3
93.3
N.A.
73.3
80
80
66.6
N.A.
20
N.A.
46.6
N.A.
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
80
86.6
86.6
73.3
N.A.
20
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
92
9
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
9
0
17
0
% E
% Phe:
0
9
0
0
9
0
84
9
0
0
0
0
0
9
0
% F
% Gly:
9
0
0
0
92
0
0
0
0
92
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
25
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
9
0
9
0
0
0
0
0
9
0
9
0
0
34
% K
% Leu:
0
84
84
0
0
17
9
0
9
0
0
34
0
0
0
% L
% Met:
84
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
9
0
92
0
0
0
0
0
0
% Q
% Arg:
0
0
0
84
0
0
0
0
0
0
0
50
0
0
59
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
9
% S
% Thr:
0
0
9
0
0
75
0
0
0
0
0
0
0
9
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
84
0
0
92
0
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _