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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CD46 All Species: 3.64
Human Site: T303 Identified Species: 20
UniProt: P15529 Number Species: 4
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P15529 NP_002380.3 392 43747 T303 A L S H S V S T S S T T K S P
Chimpanzee Pan troglodytes Q95LB0 345 38249 P267 C K A S C K V P V K K A T V V
Rhesus Macaque Macaca mulatta XP_001111498 399 44185 T303 T L S D S V S T S P T T K S P
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O88174 365 40863 W287 I C S A N N S W E P S I P K C
Rat Rattus norvegicus Q9Z0M4 355 39769 M276 F Y M E G S S M V V C G A K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.7 81.6 N.A. N.A. 45.4 46.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 35.9 87.9 N.A. N.A. 62.5 60.9 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 80 N.A. N.A. 13.3 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 80 N.A. N.A. 26.6 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 20 20 0 0 0 0 0 0 0 20 20 0 0 % A
% Cys: 20 20 0 0 20 0 0 0 0 0 20 0 0 0 20 % C
% Asp: 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 20 0 0 0 0 20 0 0 0 0 0 0 % E
% Phe: 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 20 0 0 0 0 0 0 20 0 0 0 % G
% His: 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 20 0 0 0 0 0 0 0 0 0 0 20 0 0 0 % I
% Lys: 0 20 0 0 0 20 0 0 0 20 20 0 40 40 0 % K
% Leu: 0 40 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 20 0 0 0 0 20 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 20 20 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 20 0 40 0 0 20 0 40 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 60 20 40 20 80 0 40 20 20 0 0 40 20 % S
% Thr: 20 0 0 0 0 0 0 40 0 0 40 40 20 0 0 % T
% Val: 0 0 0 0 0 40 20 0 40 20 0 0 0 20 20 % V
% Trp: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % W
% Tyr: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _