Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYP11B1 All Species: 18.48
Human Site: S350 Identified Species: 40.67
UniProt: P15538 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P15538 NP_000488.3 503 57573 S350 E S L A A A A S I S E H P Q K
Chimpanzee Pan troglodytes XP_519994 503 57708 S350 E S L A A A A S I S E H P Q K
Rhesus Macaque Macaca mulatta XP_001084565 503 57596 S350 E S L A A A A S I S E H P Q K
Dog Lupus familis XP_539192 593 66550 G440 E S Q G A Q A G I A E N P Q T
Cat Felis silvestris
Mouse Mus musculus P15539 500 57296 S350 E S L A A E A S I A A N P Q K
Rat Rattus norvegicus P30100 500 57103 S350 E T L A A E A S I A A N P Q K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512763 496 56138 G362 A A E E A G I G A N G D L L E
Chicken Gallus gallus NP_001001756 508 58177 E354 E V L A A K Q E A Q G D R V K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001073673 518 58381 Q360 Q V L S S W Q Q A S G D P L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVR9 524 60579 L360 V L S K L T S L H S E F T V E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09660 489 56052 T350 D P A S S K L T F L R A C I K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96 97.4 61.3 N.A. 67.5 68.5 N.A. 47.9 37.2 N.A. 40.9 N.A. 28.2 N.A. 25.6 N.A.
Protein Similarity: 100 97.6 98.4 72.1 N.A. 81.3 81.5 N.A. 66.1 56.2 N.A. 59.8 N.A. 46.5 N.A. 45.5 N.A.
P-Site Identity: 100 100 100 53.3 N.A. 73.3 66.6 N.A. 6.6 33.3 N.A. 26.6 N.A. 13.3 N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 66.6 N.A. 86.6 86.6 N.A. 26.6 33.3 N.A. 46.6 N.A. 26.6 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 55 73 28 55 0 28 28 19 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 28 0 0 0 % D
% Glu: 64 0 10 10 0 19 0 10 0 0 46 0 0 0 19 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 10 0 0 0 % F
% Gly: 0 0 0 10 0 10 0 19 0 0 28 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 10 0 0 28 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 55 0 0 0 0 10 0 % I
% Lys: 0 0 0 10 0 19 0 0 0 0 0 0 0 0 73 % K
% Leu: 0 10 64 0 10 0 10 10 0 10 0 0 10 19 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 0 28 0 0 0 % N
% Pro: 0 10 0 0 0 0 0 0 0 0 0 0 64 0 0 % P
% Gln: 10 0 10 0 0 10 19 10 0 10 0 0 0 55 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % R
% Ser: 0 46 10 19 19 0 10 46 0 46 0 0 0 0 0 % S
% Thr: 0 10 0 0 0 10 0 10 0 0 0 0 10 0 10 % T
% Val: 10 19 0 0 0 0 0 0 0 0 0 0 0 19 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _