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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP11B1
All Species:
12.42
Human Site:
Y81
Identified Species:
27.33
UniProt:
P15538
Number Species:
10
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15538
NP_000488.3
503
57573
Y81
E
L
G
P
I
F
R
Y
D
L
G
G
A
G
M
Chimpanzee
Pan troglodytes
XP_519994
503
57708
Y81
E
L
G
P
I
F
R
Y
N
L
G
G
P
R
M
Rhesus Macaque
Macaca mulatta
XP_001084565
503
57596
Y81
E
L
G
P
I
F
R
Y
D
L
G
G
A
G
M
Dog
Lupus familis
XP_539192
593
66550
Y171
E
L
G
P
I
F
R
Y
D
V
G
G
T
H
M
Cat
Felis silvestris
Mouse
Mus musculus
P15539
500
57296
H81
E
L
G
P
I
F
R
H
S
V
G
K
T
Q
I
Rat
Rattus norvegicus
P30100
500
57103
H81
E
L
G
P
I
F
R
H
S
A
G
G
A
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512763
496
56138
E90
Q
L
G
P
I
Y
R
E
K
L
G
K
M
T
S
Chicken
Gallus gallus
NP_001001756
508
58177
E83
R
F
G
P
I
Y
R
E
K
L
G
V
Y
E
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001073673
518
58381
E82
R
L
G
P
I
Y
R
E
H
L
G
S
Q
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVR9
524
60579
L87
D
I
C
L
I
P
G
L
F
G
M
P
S
T
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09660
489
56052
E79
K
Y
G
K
I
V
K
E
N
L
G
F
G
R
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
97.4
61.3
N.A.
67.5
68.5
N.A.
47.9
37.2
N.A.
40.9
N.A.
28.2
N.A.
25.6
N.A.
Protein Similarity:
100
97.6
98.4
72.1
N.A.
81.3
81.5
N.A.
66.1
56.2
N.A.
59.8
N.A.
46.5
N.A.
45.5
N.A.
P-Site Identity:
100
80
100
80
N.A.
53.3
66.6
N.A.
46.6
40
N.A.
46.6
N.A.
6.6
N.A.
26.6
N.A.
P-Site Similarity:
100
86.6
100
86.6
N.A.
73.3
80
N.A.
60
46.6
N.A.
53.3
N.A.
33.3
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
0
28
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
28
0
0
0
0
0
0
% D
% Glu:
55
0
0
0
0
0
0
37
0
0
0
0
0
10
0
% E
% Phe:
0
10
0
0
0
55
0
0
10
0
0
10
0
0
0
% F
% Gly:
0
0
91
0
0
0
10
0
0
10
91
46
10
19
0
% G
% His:
0
0
0
0
0
0
0
19
10
0
0
0
0
10
0
% H
% Ile:
0
10
0
0
100
0
0
0
0
0
0
0
0
0
19
% I
% Lys:
10
0
0
10
0
0
10
0
19
0
0
19
0
0
10
% K
% Leu:
0
73
0
10
0
0
0
10
0
64
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
37
% M
% Asn:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% N
% Pro:
0
0
0
82
0
10
0
0
0
0
0
10
10
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
10
19
0
% Q
% Arg:
19
0
0
0
0
0
82
0
0
0
0
0
0
19
0
% R
% Ser:
0
0
0
0
0
0
0
0
19
0
0
10
10
10
28
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
19
19
0
% T
% Val:
0
0
0
0
0
10
0
0
0
19
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
28
0
37
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _