KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNS
All Species:
17.58
Human Site:
S395
Identified Species:
42.96
UniProt:
P15586
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15586
NP_002067.1
552
62082
S395
K
T
Q
M
D
G
M
S
L
L
P
I
L
R
G
Chimpanzee
Pan troglodytes
XP_001163650
532
59970
S375
K
T
Q
M
D
G
M
S
L
L
P
I
L
R
G
Rhesus Macaque
Macaca mulatta
XP_001116940
552
62127
S395
K
T
Q
M
D
G
M
S
F
L
P
I
L
R
G
Dog
Lupus familis
XP_531660
476
54065
L320
T
Q
M
D
G
M
S
L
L
P
I
L
K
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BFR4
544
61156
S387
K
T
Q
M
D
G
M
S
L
L
P
I
L
K
G
Rat
Rattus norvegicus
Q8VI60
870
100841
V385
S
D
V
D
G
K
S
V
L
K
L
L
D
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507725
571
64833
S414
K
T
Q
M
D
G
M
S
L
L
P
L
L
R
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEX0
1114
127285
I396
Q
H
M
D
G
R
S
I
L
P
L
L
L
S
R
Honey Bee
Apis mellifera
XP_623263
506
57689
P350
M
P
S
K
I
V
A
P
V
S
S
V
D
L
F
Nematode Worm
Caenorhab. elegans
Q21376
709
83765
R417
K
L
K
K
I
R
D
R
Y
I
K
Q
K
K
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
99
83.6
N.A.
90.2
27.8
N.A.
78.9
N.A.
N.A.
N.A.
N.A.
21
40.9
31.5
N.A.
Protein Similarity:
100
96.3
99.6
84.9
N.A.
94.1
38.6
N.A.
84.7
N.A.
N.A.
N.A.
N.A.
30.7
60.1
46.5
N.A.
P-Site Identity:
100
100
93.3
6.6
N.A.
93.3
6.6
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
13.3
0
6.6
N.A.
P-Site Similarity:
100
100
93.3
13.3
N.A.
100
13.3
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
26.6
13.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
30
50
0
10
0
0
0
0
0
20
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
30
50
0
0
0
0
0
0
0
10
40
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
20
0
0
10
0
10
10
40
0
0
0
% I
% Lys:
60
0
10
20
0
10
0
0
0
10
10
0
20
20
10
% K
% Leu:
0
10
0
0
0
0
0
10
70
50
20
40
60
20
0
% L
% Met:
10
0
20
50
0
10
50
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
10
0
20
50
0
0
0
0
% P
% Gln:
10
10
50
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
20
0
10
0
0
0
0
0
40
10
% R
% Ser:
10
0
10
0
0
0
30
50
0
10
10
0
0
10
0
% S
% Thr:
10
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
10
0
10
10
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _