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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHKG2
All Species:
41.52
Human Site:
S254
Identified Species:
76.11
UniProt:
P15735
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15735
NP_000285.1
406
46442
S254
E
G
Q
Y
Q
F
S
S
P
E
W
D
D
R
S
Chimpanzee
Pan troglodytes
XP_001144282
542
61020
S390
E
G
Q
Y
Q
F
S
S
P
E
W
D
D
R
S
Rhesus Macaque
Macaca mulatta
XP_001089751
387
44961
S251
S
G
N
Y
Q
F
G
S
P
E
W
D
D
Y
S
Dog
Lupus familis
XP_848970
406
46439
S254
E
G
Q
Y
Q
F
S
S
P
E
W
D
D
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB30
406
46501
S254
E
G
Q
Y
Q
F
T
S
P
E
W
D
D
C
S
Rat
Rattus norvegicus
P31325
406
46659
S254
E
G
Q
Y
Q
F
S
S
P
E
W
D
D
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZKI0
479
54184
S235
A
G
A
Y
D
F
P
S
P
E
W
D
T
V
T
Frog
Xenopus laevis
Q9DG02
475
53914
S234
A
G
A
Y
D
F
P
S
P
E
W
D
T
V
T
Zebra Danio
Brachydanio rerio
Q6DGS3
554
62366
S234
A
G
A
Y
D
F
P
S
P
E
W
D
T
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q00168
530
59901
S235
A
G
A
Y
D
Y
P
S
P
E
W
D
T
V
T
Honey Bee
Apis mellifera
XP_623113
415
47613
S250
E
G
K
Y
S
F
T
S
P
E
W
A
D
I
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787539
414
46709
S259
E
G
R
Y
R
F
G
S
P
E
W
D
D
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FMP5
528
58466
S294
R
G
H
V
D
F
S
S
D
P
W
P
S
I
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.7
59.6
96.3
N.A.
93.3
92.6
N.A.
N.A.
30.6
29.8
28.8
N.A.
27.9
45
N.A.
47.1
Protein Similarity:
100
74.7
77.5
98.5
N.A.
95.8
96.3
N.A.
N.A.
48.6
48.6
43.1
N.A.
45
62.8
N.A.
66.9
P-Site Identity:
100
100
73.3
100
N.A.
86.6
100
N.A.
N.A.
53.3
53.3
53.3
N.A.
46.6
60
N.A.
73.3
P-Site Similarity:
100
100
73.3
100
N.A.
93.3
100
N.A.
N.A.
60
60
60
N.A.
60
80
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
0
31
0
0
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
39
0
0
0
8
0
0
85
62
0
0
% D
% Glu:
54
0
0
0
0
0
0
0
0
93
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
93
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
100
0
0
0
0
16
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
24
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
31
0
93
8
0
8
0
0
0
% P
% Gln:
0
0
39
0
47
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
8
0
8
0
0
0
0
0
0
0
0
31
0
% R
% Ser:
8
0
0
0
8
0
39
100
0
0
0
0
8
0
62
% S
% Thr:
0
0
0
0
0
0
16
0
0
0
0
0
31
0
39
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
0
31
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% W
% Tyr:
0
0
0
93
0
8
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _