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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHKG2
All Species:
31.82
Human Site:
Y358
Identified Species:
58.33
UniProt:
P15735
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P15735
NP_000285.1
406
46442
Y358
D
N
C
A
F
R
L
Y
G
H
W
V
K
K
G
Chimpanzee
Pan troglodytes
XP_001144282
542
61020
Y494
D
N
C
A
F
R
L
Y
G
H
W
V
K
K
G
Rhesus Macaque
Macaca mulatta
XP_001089751
387
44961
Y355
D
A
Y
A
F
R
I
Y
G
H
W
V
K
K
G
Dog
Lupus familis
XP_848970
406
46439
Y358
D
S
C
A
F
R
L
Y
G
H
W
V
K
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB30
406
46501
Y358
D
N
C
A
F
R
L
Y
G
H
W
V
K
K
G
Rat
Rattus norvegicus
P31325
406
46659
Y358
D
N
C
A
F
R
L
Y
G
H
W
V
K
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZKI0
479
54184
I350
V
K
A
R
K
Q
E
I
I
K
V
T
E
Q
L
Frog
Xenopus laevis
Q9DG02
475
53914
C371
F
E
A
Y
T
K
I
C
D
P
G
L
T
S
F
Zebra Danio
Brachydanio rerio
Q6DGS3
554
62366
F442
E
S
I
N
N
G
D
F
E
A
Y
A
K
I
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q00168
530
59901
K350
D
D
I
K
E
D
K
K
G
T
V
D
R
S
T
Honey Bee
Apis mellifera
XP_623113
415
47613
Y381
D
G
C
A
F
R
V
Y
G
H
W
V
K
K
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787539
414
46709
Y362
D
G
C
A
F
N
I
Y
R
H
W
V
K
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FMP5
528
58466
T467
K
D
N
S
G
Y
I
T
M
E
E
L
E
Q
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.7
59.6
96.3
N.A.
93.3
92.6
N.A.
N.A.
30.6
29.8
28.8
N.A.
27.9
45
N.A.
47.1
Protein Similarity:
100
74.7
77.5
98.5
N.A.
95.8
96.3
N.A.
N.A.
48.6
48.6
43.1
N.A.
45
62.8
N.A.
66.9
P-Site Identity:
100
100
80
93.3
N.A.
100
100
N.A.
N.A.
0
0
6.6
N.A.
13.3
86.6
N.A.
73.3
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
N.A.
20
20
33.3
N.A.
26.6
93.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
62
0
0
0
0
0
8
0
8
0
0
8
% A
% Cys:
0
0
54
0
0
0
0
8
0
0
0
0
0
0
8
% C
% Asp:
70
16
0
0
0
8
8
0
8
0
0
8
0
0
0
% D
% Glu:
8
8
0
0
8
0
8
0
8
8
8
0
16
0
0
% E
% Phe:
8
0
0
0
62
0
0
8
0
0
0
0
0
0
8
% F
% Gly:
0
16
0
0
8
8
0
0
62
0
8
0
0
0
62
% G
% His:
0
0
0
0
0
0
0
0
0
62
0
0
0
0
0
% H
% Ile:
0
0
16
0
0
0
31
8
8
0
0
0
0
8
0
% I
% Lys:
8
8
0
8
8
8
8
8
0
8
0
0
70
62
0
% K
% Leu:
0
0
0
0
0
0
39
0
0
0
0
16
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
31
8
8
8
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
16
0
% Q
% Arg:
0
0
0
8
0
54
0
0
8
0
0
0
8
0
0
% R
% Ser:
0
16
0
8
0
0
0
0
0
0
0
0
0
16
0
% S
% Thr:
0
0
0
0
8
0
0
8
0
8
0
8
8
0
8
% T
% Val:
8
0
0
0
0
0
8
0
0
0
16
62
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
62
0
0
0
0
% W
% Tyr:
0
0
8
8
0
8
0
62
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _