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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPA2 All Species: 16.97
Human Site: S12 Identified Species: 33.94
UniProt: P15927 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P15927 NP_002937.1 270 29247 S12 G F E S Y G S S S Y G G A G G
Chimpanzee Pan troglodytes XP_513251 401 43665 S143 G G F E N Y G S S Y G G A G G
Rhesus Macaque Macaca mulatta XP_001088106 261 28832 I12 G F G S Y G S I S A A D G G S
Dog Lupus familis XP_544465 368 39870 S110 G S E S Y G S S A F S G A G G
Cat Felis silvestris
Mouse Mus musculus Q62193 270 29700 S12 G F E S F T S S T Y G G R G G
Rat Rattus norvegicus Q63528 270 29327 S12 G F E S F S S S S Y G A A G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518418 244 26194
Chicken Gallus gallus NP_001026063 267 28845 G16 D G G Y G P A G G Y T Q S P G
Frog Xenopus laevis NP_001090609 274 29360 S12 Q G G F D G G S G M G G G G Y
Zebra Danio Brachydanio rerio NP_571786 272 29609 P19 M A G Y T Q S P G G F G S P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002330767 282 31111 M19 A F S G G G F M P S Q S T Q L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P26754 273 29918 T14 Y N E Y S S V T G G G F E N S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66.5 42.2 67.6 N.A. 87.4 88.8 N.A. 65.5 69.2 64.2 56.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 67.3 60 70.9 N.A. 92.2 94 N.A. 75.9 81.8 79.1 72 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 60 53.3 73.3 N.A. 73.3 80 N.A. 0 13.3 33.3 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 60 53.3 86.6 N.A. 86.6 86.6 N.A. 0 26.6 33.3 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 31.2 N.A. N.A. N.A. 21.9 N.A.
Protein Similarity: 52.1 N.A. N.A. N.A. 43.2 N.A.
P-Site Identity: 13.3 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 13.3 N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 0 0 9 0 9 9 9 9 34 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 9 0 0 0 0 0 0 9 0 0 0 % D
% Glu: 0 0 42 9 0 0 0 0 0 0 0 0 9 0 0 % E
% Phe: 0 42 9 9 17 0 9 0 0 9 9 9 0 0 0 % F
% Gly: 50 25 34 9 17 42 17 9 34 17 50 50 17 59 50 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % L
% Met: 9 0 0 0 0 0 0 9 0 9 0 0 0 0 0 % M
% Asn: 0 9 0 0 9 0 0 0 0 0 0 0 0 9 0 % N
% Pro: 0 0 0 0 0 9 0 9 9 0 0 0 0 17 0 % P
% Gln: 9 0 0 0 0 9 0 0 0 0 9 9 0 9 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % R
% Ser: 0 9 9 42 9 17 50 50 34 9 9 9 17 0 17 % S
% Thr: 0 0 0 0 9 9 0 9 9 0 9 0 9 0 0 % T
% Val: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 25 25 9 0 0 0 42 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _