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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPA2 All Species: 22.73
Human Site: S250 Identified Species: 45.45
UniProt: P15927 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P15927 NP_002937.1 270 29247 S250 K Q A V D F L S N E G H I Y S
Chimpanzee Pan troglodytes XP_513251 401 43665 S381 K Q A V D F L S N E G H I Y S
Rhesus Macaque Macaca mulatta XP_001088106 261 28832 I235 C D L S L K A I K E A I E Y L
Dog Lupus familis XP_544465 368 39870 S348 K Q A V D F L S N E G H I Y S
Cat Felis silvestris
Mouse Mus musculus Q62193 270 29700 C250 K Q A V D F L C N E G H I Y S
Rat Rattus norvegicus Q63528 270 29327 C250 K Q A V D F L C N E G H I Y S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518418 244 26194 G225 K A Y P K P E G L S F Q E L R
Chicken Gallus gallus NP_001026063 267 28845 S247 K Q A V E F L S S E G H I Y S
Frog Xenopus laevis NP_001090609 274 29360 S254 R K T V D F L S N E G H I Y S
Zebra Danio Brachydanio rerio NP_571786 272 29609 S250 R Q T V D F L S N E G H Q Y V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002330767 282 31111 K256 Q L K L P M E K I K E S I R S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P26754 273 29918 T247 S L N L D E T T V R N C C T T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66.5 42.2 67.6 N.A. 87.4 88.8 N.A. 65.5 69.2 64.2 56.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 67.3 60 70.9 N.A. 92.2 94 N.A. 75.9 81.8 79.1 72 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 13.3 100 N.A. 93.3 93.3 N.A. 6.6 86.6 80 73.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 100 N.A. 93.3 93.3 N.A. 6.6 100 93.3 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 31.2 N.A. N.A. N.A. 21.9 N.A.
Protein Similarity: 52.1 N.A. N.A. N.A. 43.2 N.A.
P-Site Identity: 13.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 33.3 N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 50 0 0 0 9 0 0 0 9 0 0 0 0 % A
% Cys: 9 0 0 0 0 0 0 17 0 0 0 9 9 0 0 % C
% Asp: 0 9 0 0 67 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 9 9 17 0 0 75 9 0 17 0 0 % E
% Phe: 0 0 0 0 0 67 0 0 0 0 9 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 9 0 0 67 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 67 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 9 9 0 0 9 67 0 0 % I
% Lys: 59 9 9 0 9 9 0 9 9 9 0 0 0 0 0 % K
% Leu: 0 17 9 17 9 0 67 0 9 0 0 0 0 9 9 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 59 0 9 0 0 0 0 % N
% Pro: 0 0 0 9 9 9 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 59 0 0 0 0 0 0 0 0 0 9 9 0 0 % Q
% Arg: 17 0 0 0 0 0 0 0 0 9 0 0 0 9 9 % R
% Ser: 9 0 0 9 0 0 0 50 9 9 0 9 0 0 67 % S
% Thr: 0 0 17 0 0 0 9 9 0 0 0 0 0 9 9 % T
% Val: 0 0 0 67 0 0 0 0 9 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 0 0 0 0 75 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _