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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPR1
All Species:
19.09
Human Site:
T546
Identified Species:
38.18
UniProt:
P16066
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16066
NP_000897.3
1061
118919
T546
N
Y
G
S
L
L
T
T
E
G
Q
F
Q
V
F
Chimpanzee
Pan troglodytes
XP_001168194
1047
116964
A530
S
Y
G
S
L
M
T
A
H
G
K
Y
Q
I
F
Rhesus Macaque
Macaca mulatta
XP_001085221
1047
116990
A530
S
Y
G
S
L
M
T
A
H
G
K
Y
Q
I
F
Dog
Lupus familis
XP_547577
1060
118154
T545
N
Y
G
S
L
L
T
T
E
G
Q
F
Q
V
F
Cat
Felis silvestris
Mouse
Mus musculus
P18293
1057
119091
T542
N
Y
G
S
L
L
T
T
E
G
Q
F
Q
V
F
Rat
Rattus norvegicus
P18910
1057
118933
T542
N
Y
G
S
L
L
T
T
E
G
Q
F
Q
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517544
743
84256
A281
H
L
T
R
F
I
G
A
C
I
D
P
P
N
I
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001083703
1056
120483
T540
N
Y
G
S
L
I
T
T
E
G
Q
F
Q
I
Y
Zebra Danio
Brachydanio rerio
NP_001038402
1067
121798
M552
N
Y
G
S
L
L
T
M
D
G
N
F
Q
I
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07553
1163
130896
G538
R
Q
S
I
L
V
V
G
E
P
N
K
R
S
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09435
1137
128085
T571
S
T
G
H
S
G
V
T
T
V
S
D
F
C
E
Sea Urchin
Strong. purpuratus
P16065
1125
126238
N579
S
A
I
S
V
I
S
N
A
E
K
Q
Q
I
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.2
61.2
91.6
N.A.
90.8
90.8
N.A.
48.5
N.A.
66.1
62.7
N.A.
31.5
N.A.
29.8
35.1
Protein Similarity:
100
73.8
73.8
95
N.A.
94.2
94.2
N.A.
58.6
N.A.
78.7
77.5
N.A.
47.8
N.A.
49
50.8
P-Site Identity:
100
53.3
53.3
100
N.A.
100
100
N.A.
0
N.A.
80
66.6
N.A.
20
N.A.
13.3
20
P-Site Similarity:
100
86.6
86.6
100
N.A.
100
100
N.A.
13.3
N.A.
100
86.6
N.A.
33.3
N.A.
20
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
25
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
0
9
9
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
50
9
0
0
0
0
9
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
50
9
0
67
% F
% Gly:
0
0
75
0
0
9
9
9
0
67
0
0
0
0
0
% G
% His:
9
0
0
9
0
0
0
0
17
0
0
0
0
0
0
% H
% Ile:
0
0
9
9
0
25
0
0
0
9
0
0
0
42
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
25
9
0
0
0
% K
% Leu:
0
9
0
0
75
42
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
17
0
9
0
0
0
0
0
0
0
% M
% Asn:
50
0
0
0
0
0
0
9
0
0
17
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
9
9
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
42
9
75
0
0
% Q
% Arg:
9
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% R
% Ser:
34
0
9
75
9
0
9
0
0
0
9
0
0
9
0
% S
% Thr:
0
9
9
0
0
0
67
50
9
0
0
0
0
0
0
% T
% Val:
0
0
0
0
9
9
17
0
0
9
0
0
0
34
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
67
0
0
0
0
0
0
0
0
0
17
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _